Study Type
Interventional - Procedure
completed
The objective of the HIP ATTACK Pilot study was to determine the feasibility and resource requirements of accelerated surgery and medical clearance as well as recruitment and follow-up of study participants.
The primary outcome of the pilot study was to evaluate the feasibility of enrolling 60 patients and achieving arrival into the operating room within six hours of diagnosis in 80 percent of patients randomized to accelerated surgery.
Primary outcome measure:
Feasibility.
Secondary outcome measures:
Composite of mortality, nonfatal myocardial infarction, nonfatal pulmonary embolism, nonfatal pneumonia, nonfatal sepsis, nonfatal stroke, and nonfatal life-threatening and major bleeding.
The Co-Principal Investigator on the HIP ATTACK Pilot study was Mohit Bhandari.
Study Design
Randomized controlled, parallel group, pilot trial
NO. of Countries
2
NO. of Sites
3
NO. of Participants
60
Study Period
2011-2012
Sponsor
PHRI
PJ Devereaux
Senior Scientist
PJ Devereaux
Senior Scientist
PJ Devereaux is Senior Scientific Lead, Perioperative and Surgery, PHRI, Professor and University Scholar in the Departments of Health Research Methods, Evidence, and Impact (HEI) and Medicine at McMaster University, and Director of the Division of Cardiology at McMaster.
The focus of his clinic research is vascular complications around the time of surgery, leading several large, international RCTs and observational studies addressing this issue. He has published more than 250 peer-reviewed papers and more than 50 book chapters and editorials. He is supported by a Tier 1 Canadian Research Chair in Perioperative Medicine, and holds the Yusuf Chair in Cardiology at McMaster University.
Jessica Vincent
Program Director
Jessica Vincent
Program Director
Jessica Vincent has more than 15 years’ experience in coordinating and managing large, international clinical trials. As Associate Program Manager, she oversees interventional trials, registries, and observational research studies in the areas of perioperative medicine, cardiac surgery, and digital health.
She holds an Honours Bachelor of Science Degree from Queens University, and a Master of Clinical Epidemiology Degree from the University of Newcastle.
Hamilton Academic Health Sciences Organization (HAHSO)
Octapharma Canada Incorporated Grant
ongoing
HIP ATTACK-2
Perioperative & Surgery
The HIP ATTACK-2 trial is a multicentre, international, parallel group randomized controlled trial to determine...
completed
HIP ATTACK-1
Perioperative & Surgery
A hip fracture causes bleeding, pain and immobility, and initiates inflammatory, hypercoagulable, catabolic and stress...
completed
FAST Pilot
Perioperative & Surgery
The prevalence of gallstones is 10-20% among Canadians. About 10% of these patients develop Acute...
