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Research > Perioperative & Surgery

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FAST Pilot

Official Title

Fast track pathway to Accelerated cholecystectomy versus Standard of care for acute cholecysTitis

Status

Ongoing

Overview

Among patients with acute cholecystitis (AC), to determine if a trial of accelerated surgery (i.e, as soon as possible with a goal of surgery within 6 hours of diagnosis) compared to usual care is feasible.

Study Design

Multicentre, parallel group Randomized Controlled Trial (RCT)

Primary Endpoint

Feasibility of a large-scale trial as defined by:
1. Recruitment of 60 patients across the 3 participating sites. We will judge recruitment as feasible if each site can randomize 1 patient per month
2. ≥95% follow-up at 90 days post-randomization; and
3. Proportion of patients randomized to accelerated surgery receiving surgery within 6 hours following the diagnosis of acute cholecystitis.

Number of Patients

60

Number of Sites

3

Number of Countries

1

Study Period

2019-2020

Principal Investigator

PJ Devereaux

Program Manager

Shirley Pettit