Research > Heart Failure

INTER-CHF

Official Title

An international registry to study the current causes, treatment, barriers to care, and outcome of heart failure in Africa, Asia and South America

Status

Completed

Overview

This heart failure (HF) registry in Africa, Asia and South America will gather information on the current status of HF etiology, treatment, potential barriers to evidence-based care, and outcome in these rapidly developing regions of the world. The collected information will help fill in important gaps in the understanding of HF globally.

Study Design

A prospective, international, multicenter cross-sectional study, including a longitudinal component.  The registry will be both descriptive and analytical by attempting to develop prognostic stratification based on features at baseline and the occurrence of outcome events at 6 and 12 months’ follow-up.

Primary Endpoint

All-cause mortality at 1-year

Number of Patients

5800

Number of Sites

108

Number of Countries

16

Study Period

2012-2015

Principal Investigator

Hisham Dokainish

Program Manager

Kimberly Begley

Research Coordinator

Alex Grinvalds

Key Publications

Dokainish H, Teo K, Zhu J, Roy A, AlHabib KF, ElSayed A, Palileo-Villaneuva L, Lopez-Jaramillo P, Karaye K, Yusoff K, Orlandini A, Sliwa K, Mondo C, Lanas F, Prabhakaran D, Badr A, Elmaghawry M, Damasceno A, Tibazarwa K, Belley-Cote E, Balasubramanian K, Yacoub MH, Huffman MD, Harkness K, Grinvalds A, McKelvie R, Yusuf S; INTER-CHF Investigators. Global mortality variations in patients with heart failure: results from the International Congestive Heart Failure (INTER-CHF) prospective cohort study. Lancet Glob Health 2017; 5(7): e665-e672.

Dokainish H, Teo K, Zhu J, Roy A, AlHabib KF, ElSayed A, Palileo-Villaneuva L, Lopez-Jaramillo P, Karaye K, Yusoff K, Orlandini A, Sliwa K, Mondo C, Lanas F, Prabhakaran D, Badr A, Elmaghawry M, Damasceno A, Tibazarwa K, Belley-Cote E, Balasubramanian K, Yacoub MH, Huffman MD, Harkness K, Grinvalds A, McKelvie R, Yusuf S; INTER-CHF Investigators. Heart Failure in Africa, Asia, the Middle East and South America: The INTER-CHF study. Int J Cardiol 2016; 204: 133-41.