completed

The objective of the TIPS study was to assess the efficacy and safety of the POLYCAP, a fixed dose combination containing five drugs (an antiplatelet drug; 3 blood pressure lowering agents, a beta blocker, an ACE inhibitor, a diuretic and a statin.)

TIPS was the first completed trial of a polypill, and tests primarily the feasibility and pharmacological effects of various polypill preparations.

Primary endpoints:

Reduction in blood pressure

Reduction in heart rate

Modify lipids

Secondary endpoint: Platelet aggregation. Not adjudicated

The Co-Principal Investigator on the TIPS study was Prem Pais, Professor of Medicine, St. John’s Research Institute, India.

Study Type

Interventional - Drug

Study Design

Randomized, double-blind, active control, parallel group design, safety/efficacy study.

NO. of Countries

1

NO. of Sites

70

NO. of Participants

2050

Study Period

2007-2009

Sponsor

PHRI

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