Recent Publications

CAHHM, PURE Mind: Association of dietary macronutrients with MRI-detected vascular brain injury and cognition in 9886 middle-aged participants from four countries

eClinicalMedicine

Victoria Miller, Eric Smith, Karleen M. Schulze, Dipika Desai, Vikki Ho, Trevor J. B. Dummer, Jean-Claude Tardif, Scott Lear, Paul Poirier, Hassan Mir,l Kook K. Teo, Katarzyna Zatonska, Andrzej Szuba, Anna Zimny, Dorota Szczes´niak, Thomas Iype, Wei Li, Raed Joundi, Andrew Mente,Matthias G. Friedrich, Russell J. de Souza, Salim Yusuf, and Sonia S. Anand

July 2025

COMPASS, ORIGIN, TRANSCEND: Comparison of total event analysis and first event analysis in relation to heterogeneity in cardiovascular trials

BMC Medical Research Methodology

Lee SF, Ramasundarahettige C, Gerstein HC, McIntyre WF, Eikelboom J, O'Donnell MJ, Zhou Y, Bangdiwala SI, Thabane L

June 2025

RE-LY F Registry: Alcohol Intake and Cardiovascular Outcomes in Patients With Atrial Fibrillation

Annals of Noninvasive Electrocardiology

Oraii A, Conen D, Johnson LS, McIntyre WF, Kirabo F, Balasubramanian K, Benz AP, Oldgren J, Nielsen JC, Healey J

June 2025

ACHIEVE: The Aldosterone Blockade for Health Improvement Evaluation in End-Stage Renal Disease Trial: Rationale and Clinical Research Protocol

Canadian Journal of Kidney Health and Disease

Walsh M, Collister D, Gallagher M, Mark PB, de Zoysa JR, Tyrwhitt J, Tennankore K, Sola L, Reis G, Xavier D, Villanueva R, Liu WJ, Félix C, Zuo L, Arici M, Jha V, Wald R, Wang AY, Faruqui AR, Yuan F, Lee SF, Kuptsova A, Christou C, Devereaux PJ; ACHIEVE Investigators.

June 2025

POISE-3: Effects of a Hypotension-Avoidance Versus a Hypertension-Avoidance Strategy on Neurocognitive Outcomes After Noncardiac Surgery

Annals of Internal Medicine

Marcucci M, Chan MTV, Painter TW, Efremov S, Aguado HJ, Astrakov SV, Kleinlugtenbelt YV, Patel A, Cata JP, Amir M, Kirov M, Leslie K, Duceppe E, Borges FK, de Nadal M, Tandon V, Landoni G, Likhvantsev VV, Lomivorotov V, Sessler DI, Martínez-Zapata MJ, Xavier D, Fleischmann E, Wang CY, Meyhoff CS, Wittmann M, Torres D, Highton D, Jacka M, B V, Zarnke K, Sidhu RS, Oriani G, Ayad S, Minear S, Weaver TE, Ruetzler K, Brusasco C, Parlow JL, Maxwell E, Miller S, Mrkobrada M, Bhatt KSC, Rahate P, Kowark A, De Blasio G, Ofori SN, Conen D, Srinathan S, Szczeklik W, Jayaram R, Ellerkmann RK, Momeni M, Copland I, Vincent J, Balasubramanian K, Li Z, Wang MK, Li D, McGillion MH, Kurz A, Sharma M, Short TG, Devereaux PJ, cogPOISE-3 Trial Investigators and Study Groups.

June 2025

PVC-RAM-3: Impact of Virtual Care With Remote Automated Monitoring on the Rate of Acute Hospital Care Post Discharge and Index Length of Hospital Stay

JMIR Research Protocols

Ofori S, McGillion MH, Borges FK, Ouellette C, Patel A, Conen D, Marcucci M, Wang MK, Park LJ, Bell C, Lounsbury J, Nagatani K, Tandon V, Wilkieson TJ, Wyne A, Harvey V, Harrison S, Nenshi R, Bogach J, Harlock J, Cadeddu M, Forbes S, Haider S, Mirza RD, Narang S, Reade CJ, Tushinski DM, Raut A, Raza S, Scott T, Adili A, Petch J, Devereaux PJ

June 2025

PURE-China: Long-term exposure to outdoor fine particulate and physical activity with mortality and cardiovascular events

The Lancet Regional Health – Western Pacific

Hao J, Liu Z, Hu B, Wang D, Rangarajan S, Wang Y, Wang C, Tse LA, Liu W, Li S, Yan M, Cai Q, Yusuf S, Li W; PURE-China Investigators

May 2025

VISION Cardiac Surgery: Polygenic risk scores for risk prediction of atrial fibrillation in cardiac surgery patients: Insights from the prospective, multinational cohort

EP Europace

W F Mcintyre, M Chong, P J Devereaux, K Brady, S Bashir, T Sun, A Lamy, J D Roberts, G Pare, M T V Chan, C Y Wang, A Singh, E P Belley-Cote, R P Whitlock, J D Spence

May 2025

VISION: Derivation and internal-external validation of clinical prediction model for postoperative clinically important hypotension in patients undergoing noncardiac surgery: an international prospective cohort study

British Journal of Anaesthesia Open

Yang SS, Malaga G, Lazo-Porras M, Busta-Flores P, Del Carmen Rotta-Rotta A, Roshanov PS, Sessler DI, Bessissow A, Schricker T, Tagalakis V, Heels-Ansdell D, Pettit S, Devereaux PJ

May 2025

PREMISE: Efficacy and Safety of Transcatheter Mitral Valve Edge-to-Edge Repair with Mitraclip in Real-World Canadian Practice

CJC Open

Shamir R. Mehta, Anita Asgar, Robert Boone, Josep Rodes-Cabau, Eric A. Cohen, Andrew Czarnecki, Marino Labinaz, Shahar Lavi, Nicolo Piazza, Kevin R. Bainey, Akshay Bagai, Jean-Michel Paradis, J.D. Schwalm, Douglas Wright, Helen Nguyen, Tara McCready, Rajibul Mian, John Webb, Neil Fam

May 2025

TIMACS: Sex differences based on the timing of invasive management among patients with non-ST-elevation acute coronary syndrome: an individual patient data meta-analysis

European Heart Journal Open

Graziella Pompei, Gregory B Mills, Christos P Kotanidis, Shamir Mehta, Denise Tiong, Erik A Badings, Thomas Engstrøm, Arnoud W J van‘t Hof, Dan Høfsten, Lene Holmvang, Alexander Jobs, Lars Køber, Dejan Milasinovic, Aleksandra Milosevic, Goran Stankovic, Holger Thiele, Roxana Mehran, Vijay Kunadian

June 2025

INTERBLEED: Risk factors associated with gastrointestinal bleeding in patients with cardiovascular disease: a case control study

European Journal of Preventive Cardiology

Bosch J, O'Donnell M, Yi Q, Moayyedi P, Alings M, Avezum A, Bangdiwala SI, Barkun A, Cassella F, Marchi da Rocha A, Duzen I, Enns R, Forbes N, Hamilton L, Kilickap M, Kruger P, Liang Y, Nicolau JC, Nunes RB, Oliviera G, Rey A, Shofiqul I, Sun Y, Vanassche T, Verhamme P, Walsh M, Wang Z, Wu C, Zhao L, Zhu J, Eikelboom JW.

May 2025

VISION: The CLUE Post-Surgery VTE Risk Instrument for Abdominal and Pelvic Surgery: Validation of Patient Risk Factor Component.

Blood Advances

Tikkinen KAO, Siegal DM, Devereaux PJ, Tornberg SV, Borges FK, Ofori S, Pinthus J, Shayegan B, Lavikainen LI, Guyatt GH, Roshanov PS

May 2025

PACIFIC-STROKE: Hemorrhagic Transformation in Noncardioembolic Acute Ischemic Stroke: MRI Analysis

Stroke

Chen CH, Shoamanesh A, Colorado P, Saad F, Lemmens R, De Marchis GM, Caso V, Xu L, Heenan L, Masjuan J, Christensen H, Connolly SJ, Khatri P, Mundl H, Hart RG, Smith EE

May 2025

PACIFIC-STROKE: Location, size, and risk factors of incident covert brain infarcts in patients with acute non-cardioembolic ischemic stroke

European Stroke Journal

Hart RG, Smith EE, Wang A, Mundl H, Colorado P, Joundi RA, Katsanos AH, Sharma M, Shoamanesh A.

June 2025

eClinicalMedicine

BMC Medical Research Methodology

Annals of Noninvasive Electrocardiology

Canadian Journal of Kidney Health and Disease

Annals of Internal Medicine

JMIR Research Protocols

The Lancet Regional Health – Western Pacific

EP Europace

British Journal of Anaesthesia Open

CJC Open

European Heart Journal Open

European Journal of Preventive Cardiology

Blood Advances

Stroke

European Stroke Journal

Sign up for the PHRI Pulse Newsletter