Recent Publications

STRIVE: Intracoronary Low-Dose Recombinant Tissue Plasminogen Activator in Primary PCI for ST-Segment Elevation Myocardial Infarction and Large Thrombus Burden: A Randomized Trial

Journal of the American College of Cardiology

Shamir R. Mehta, Natalia Pinilla-Echeverri, Denise Tiong, Tanya Kovalova, Tej Sheth, Madhu K. Natarajan, Matthew Sibbald, James L. Velianou, Robert Welsh, Bryan Har, Sanjit S. Jolly, Nicholas Valettas, J.D. Schwalm, Michael Tsang, Rutaba Khatun, Rajibul Mian, Jennifer Cunningham, Eric Ly BHK, Tara McCready, and Kevin R. Bainey

October 2025

COMPLETE: Impact of complete revascularisation in relation to left ventricular function in patients with ST-segment elevation myocardial infarction and multivessel disease: a post hoc analysis

EuroIntervention

Tiong D, Pinilla-Echeverri N, Wood DA, Mehran R, Storey RF, Feldman L, Moreno R, Rao S, Cantor WJ, Welsh R, Bainey KR, Cohen EA, Tsang MB, Sibbald M, Natarajan MK, Wijesena D, Mani T, Nguyen H, Cairns JA, Mehta SR

October 2025

LEADER-PAD: Low Dose Colchicine in Patients with Peripheral Artery Disease to Address Residual Vascular Risk Trial: Relevance and Importance of a Global Initiative

European Journal of Vascular and Endovascular Surgery

Jansen S, Chan N, de Borst GJ, Hinchliffe R, Vemulapalli S, Teraa M; LEADER-PAD Study Group.

September 2025

CLEAR SYNERGY: Benefit–risk of colchicine and spironolactone in acute myocardial infarction: a prespecified generalised pairwise comparisons analysis of the CLEAR trial

Heart

d'Entremont MA, Jolly SS, Alharthi F, Shah B, Austin D, Yi Q, Storey RF, Bossard M, Cornel J, Jaspers Focks J, Kedev S, Asani V, Stankovic G, Tsang M, Valettas N, Tyrwhitt J, Betz J, Lee SF, Mian R, Silvain J, Beygui F, Czarnecki A, Dehghani P, Cantor W, Lavi S, Spratt JC, Belley-Côté EP, Eikelboom JW.

September 2025

LAAOS III: Oral anticoagulation in patients with atrial fibrillation and heart valve prosthesis: A substudy from the Left Atrial Appendage Occlusion Study

The Journal of Thoracic and Cardiovascular Surgery

Paparella D, Belley-Cote EP, Di Mauro M, Squiccimarro E, Macella M, Brady K, Chu MWA, Whitlock RP.

September 2025

PACIFIC-STROKE: Dual versus single antiplatelet therapy in patients with non-cardioembolic acute ischemic stroke and baseline MRI

European Stroke Journal

De Marchis GM, Toebak A, Dittrich T, Vlachos D, Wang A, Smith EE, Mundl H, Colorado P, Shoamanesh A, Hart RG.

September 2025

PACT-HF: Long-Term Healthcare Utilization and Outcomes in Patients Hospitalized for Heart Failure With and Without Atrial Fibrillation

American Journal of Cardiology

Verelst FR, Zagorski B, Averbuch T, Bagur R, Granger C, Gevaert AB, Van Spall HGC.

August 2025

ARTESiA: Cost-effectiveness of apixaban vs. aspirin for the reduction of thrombo-embolism in high-risk patients with device-detected atrial fibrillation

EP Europace

Lamy A, Sandhu RK, Tong W, McIntyre WF, Lopes RD, Granger CB, Wright DJ, Nielsen JC, Kutyifa V, Erath JW, Alings M, Birnie DH, Atar D, Hohnloser SH, Linde C, Kautzner J, Benezet-Mazuecos J, Camm AJ, Sticherling C, Gold MR, Larroudé CE, Healey JS.

August 2025

ARCADIA: Heart Rhythm Monitoring Practices, Detection of Atrial Fibrillation, and Effect of Anticoagulation in the ARCADIA Trial

Journal of the American Heart Association

Kamel H, Elkind MSV, Kronmal RA, Aragon Garcia R, Plummer P, Broderick JP, Pauls Q, Elm JJ, Di Tullio MR, Soliman EZ, Healey JS, Yaghi S, Burton TM, Tirschwell DL, Longstreth WT Jr; ARCADIA Investigators.

August 2025

PURE: Ultraprocessed Grains and Risk of Inflammatory Bowel Disease

The American Journal of Gastroenterology

Narula N, Wong ECL, Mente A, Rangarajan S, Lang X, Li Q, Chen M, Mohan I, Mat-Nasir N, Diaz ML, Lopez-Jaramillo P, Bahonar A, Avezum A, Karsidag K, Rosengren A, Abat MEM, Lanas F, Swart EC, Yusuf R, Alhabib KF, Iqbal R, Basiak-Rasała A, Khatib R, Yusufali A, Yeates K, Chifamba J, Marshall JK, Moayyedi P, Reinisch W, Yusuf S.

August 2025

ORIGIN: Can a Combined Epigenetic-Biomarker Score Supplant Chronologic Age as an Independent Determinant of Incident Death in Adults with Dysglycemia

Canadian Journal of Diabetes

Gerstein HC, Pare G, Zhou K, Yang S, Chong M, Steinberg GR, Lee SF.

August 2025

AMPLITUDE-O: Effect of Efpeglenatide on Heart Failure Outcomes: A Participant-Level Exploratory Analysis

Diabetes Care

Branch KRH, Lam CSP, Islam S, Del Prato S, Lopes RD, Pratley R, Rosenstock J, Sattar N, Gerstein HC.

August 2025

ARTESiA: Apixaban for stroke prevention in subclinical atrial fibrillation detected by an implantable cardiac monitor: A subgroup analysis

Heart Rhythm

Xing LY, Lopes RD, McIntyre WF, Sandhu RK, Rubio Campal JM, Khoo C, Granger CB, Gold MR, Svendsen JH, Diederichsen SZ, Alings M, Mabo P, Kutyifa V, Nielsen JC, Birnie DH, Benz AP, Mani T, Ramasundarahettige C, Healey JS; ARTESiA investigators (NCT01938248).

July 2025

PURE: Social factors, health policy, and environment: implications for cardiovascular disease across the globe

European Heart Journal

Lear SA, McKee M, Hystad P, Walker BB, Murphy A, Brauer M, Walli-Attaei M, Rosengren A, Rangarajan S, Chow CK, Yusuf S.

August 2025

COMPASS MIND: Atrial fibrillation and atherosclerosis cause different vascular brain lesions on magnetic resonance imaging

European Heart Journal

Stegmann T, Joundi RA, Srivastava A, Sinnecker T, Aeschbacher S, Eikelboom JW, Wachter R, Smith EE, Rodondi N, Bosch J, Blum MR, Connolly SJ, Beer JH, Reeh KW, Reichlin T, Lonn EM, Yi Q, Müller AS, Branch KRH, Di Valentino M, Avezum A, Fox KAA, Ammann P, Bonati LH, Moschovitis G, Krisai P, Kühne M, Osswald S, Sharma M, Conen D.

September 2025

Journal of the American College of Cardiology

EuroIntervention

European Journal of Vascular and Endovascular Surgery

Heart

The Journal of Thoracic and Cardiovascular Surgery

European Stroke Journal

American Journal of Cardiology

EP Europace

Journal of the American Heart Association

The American Journal of Gastroenterology

Canadian Journal of Diabetes

Diabetes Care

Heart Rhythm

European Heart Journal

European Heart Journal

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