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Research

Photo for LAAOS II

LAAOS II

Official Title

Left Atrial Appendage Occlusion Study

Status

Completed

Overview

To compare efficacy of LAA exclusion (during cardiac surgery) and aspirin therapy versus best medical therapy as per guidelines in reducing risk of stroke in AF patients undergoing cardiac surgery.

Study Design

Randomized controlled, open label, multicenter, study.

Primary Endpoint

Feasibility.

Number of Patients

51

Number of Sites

4

Number of Countries

1

Study Period

2009–2012

Principal Investigator

Richard Whitlock

Program Manager

Susan Chrolavicius

Research Coordinator

Jessica Vincent

Key Publications

  • Whitlock RP, Vincent J, Blackall MH, Hirsh J, Fremes S, Novick R, Devereaux PJ, Teoh K, Lamy A, Connolly SJ, Yusuf S, Carrier M, Healey JS. Left Atrial Appendage Occlusion Study II (LAAOS II). Can J Cardiol. 2013 Nov;29(11):1443-7. doi: 10.1016/j.cjca.2013.06.015.