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Research

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IMAGINE

Official Title

Inflammation, Microbiome, and Alimentation: Intestinal and Neuropsychiatric Effects: the IMAGINE-SPOR chronic disease network

Status

Ongoing

Overview

To create a large cohort of patients with Irritable Bowel Syndrome (IBS), Inflammatory Bowel Disease (IBD) and healthy controls and follow these individuals over time, collecting patient information using validated questionnaires and stool, urine and blood samples, to correlate their GI and psychological symptoms with their diet, microbiome and its metabolome.

Study Design

Observational prospective cohort

Primary Endpoint

To better understand the key mechanisms in diet-microbiome-host relationship that will allow for better targeted treatment of IBD and IBS and the psychiatric disorders associated with these diseases.

Number of Patients

8000

Number of Sites

17

Number of Countries

1

Study Period

2017-2023

Principal Investigator

Paul Moayyedi (McMaster University); Glenda MacQueen (University of Calgary)

Program Manager

Tara McCready

Research Coordinator

Jennifer Cunningham

Collaborators

The IMAGINE Chronic Disease Network, Strategy for Patient Oriented Research (SPOR), Canadian Institutes of Health Research (CIHR)

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