Flavia Kessler Borges
Flavia Kessler Borges
Flavia Borges is a Scientist in the perioperative and surgery research group at PHRI, and internist, and an Assistant Professor, Department of Medicine (perioperative care; general internal medicine), McMaster University. Her research is focused on perioperative cardiac biomarkers, and perioperative strategies to improve clinical outcomes in patients undergoing noncardiac surgery.
She undertook her Masters in Health Sciences and her PhD in Cardiovascular Sciences in Brazil, and a research and clinical perioperative vascular fellowship under the direction of PJ Devereaux at McMaster. She holds an Early Career Research Award from McMaster.
Jackie Bosch started working with Salim Yusuf in 1993, before PHRI was formally created, as she was completing her Masters in Clinical Epidemiology, with the intent to learn how to do clinical trials so she could run trials in post-stroke rehabilitation. Most recently, she has been a co-investigator on large trials in primary and secondary prevention of cardiovascular disease and diabetes, as well as understanding the causes of functional decline as well as developing simple, internationally applicable interventions to improve post-stroke disability.
She is Assistant Dean of the Occupational Therapy program, School of Rehabilitation Sciences, McMaster University, and has received awards such as the (McMaster) President’s Award for Outstanding Service, and the PHRI Award for Outstanding Contributions to Global Collaborations. She has more than 65 peer-reviewed publications.
Noel Chan is an Assistant Professor in the Division of Hematology and Thromboembolism, Department of Medicine, McMaster University, specializing in anticoagulant therapy and thrombosis medicine. His research seeks to improve our understanding of the triggers for thrombosis (including the role of inflammation) and the determinants of variable response to antithrombotic therapies to inform on novel strategies that have the potential to further reduce the burden of thrombosis.
David Conen is a Scientist at PHRI, which he joined in 2016, and an Associate Professor, Department of Medicine, McMaster University. A trained internist and cardiologist from Basel, Switzerland, he obtained a Master of Public Health degree from Harvard University.
His research activities involves the conduct of large epidemiological cohort studies to study risk factors for the occurrence of atrial fibrillation and its consequences, and research into therapies to prevent and treat perioperative atrial fibrillation. David is the Co-Principal Investigator of a large national cohort study to assess the relationship between atrial fibrillation and cognitive decline in Switzerland (Swiss-AF). He has published more than 130 peer-reviewed manuscripts in leading scientific journals as well as several reviews and editorials.
Sanjit Jolly is an interventional cardiologist at Hamilton Health Sciences and associate professor at McMaster University. He has formal training in clinical trials with a M.Sc. in Health Research Methodology from McMaster. He was the principal investigator of the RIVAL trial, a randomized trial of 7021 patients comparing radial and femoral access for coronary intervention. He is also the principal investigator trial of the ongoing TOTAL trial, an international randomized trial (N=10,700) of thrombectomy during primary PCI.
Philip Joseph’s research interests include cardiovascular prevention, global health, heart failure, and cardiac imaging. He is the principal investigator for the PURE-AF substudy, and the SPECT-MINS study, an investigator in the PURE study, and the G-CHF registry. He is also the project officer for the TIPS-3 study. He has published more than 30 peer-reviewed scientific papers.
He is a fellow of the Royal College of Physicians and Surgeons of Canada, with certification in both internal medicine and cardiology. obtained his B.A.Sc at McMaster University in 2000, and his M.D. at Western University in 2004. His internal medicine (2004-2007) and cardiology (2007-2010) residencies were completed at the University of Ottawa. Subsequently, he completed additional clinical training in Nuclear Cardiology at McMaster University (2013), a M.Sc. in Health Research Methodology at McMaster (2010-13), and a post-doctoral research fellowship in PET imaging at Harvard University (2015).
Maura Marcucci is a scientist in the Perioperative and Surgery research group at PHRI, and an Assistant Professor, Department of Medicine, and Department of Health Research Methods, Evidence, and Impact, at McMaster University. Leveraging on her background in vascular medicine, thrombosis and hemostasis disorders, and geriatrics, Maura’s current main focus of clinical research is cardiovascular and neurocognitive outcomes in noncardiac surgery. She is currently the project officer of the PeriOperative ISchemic Evaluation (POISE)-3 trial and principal investigator of the POISE-3 sub-study on delirium and cognitive decline.
She obtained her medical training and residency in Internal Medicine in Italy. In 2012-2013 she completed an MSc in Health Research Methodology and a clinical fellowship in Hematology/Medicine at McMaster University. In 2014-2016 she was an Assistant Professor at the University of Milan in Italy, before returning to Hamilton, Canada.
Andre Lamy is a cardiac surgeon practicing at the Hamilton Health Sciences since 1996, and Professor in the Department of Surgery, McMaster University. He led the Canadian Institute of Health Research funded CORONARY trial, which evaluated off-pump CABG surgery versus on-pump CABG surgery in 4752 patients. The results were published in the New England Journal of Medicine in 2012 and 2013.
Darryl Leong is a Scientist at PHRI, Director of the McMaster University and Hamilton Health Sciences Cardio-Oncology Program, Associate Professor, Department of Medicine (Cardiology), McMaster University, and Staff Cardiologist at Hamilton Health Sciences. He has methodological expertise in clinical epidemiology and clinical trials, and content expertise in physical frailty, echocardiography, and cardio-oncology. His research is supported by the CIHR, and he has published more than 150 manuscripts including all the leading internal medical and cardiovascular journals.
He graduated from the University of Adelaide Medical School with Deans Listing and Honours for academic excellence, completed his cardiology training, Doctor of Philosophy, Master of Public Health, and Master of Biostatistics degrees at the University of Adelaide in Australia, and completed a post-doctorate fellowship in cardiovascular imaging at the Leiden University Medical Centre in The Netherlands, before re-locating to Canada.
Michael McGillion is Associate Professor, and Assistant Dean, Research, at the School of Nursing, McMaster University. He is the Heart and Stroke Foundation/Michael G. DeGroote Endowed Chair in Cardiovascular Nursing Research, and the International Visiting Professor of Digital Health, at Coventry University in the UK.
He is an internationally-recognized researcher in the area of persistent forms of cardiac pain such as refractory angina and unrelieved chest pain following successful revascularization procedures. He was Chair of the Joint Canadian Cardiovascular Society – Canadian Pain Society guidelines for the management of refractory angina, funded by the Canadian Institutes of Health Research (CIHR). He is Principal Investigator of the largest CIHR-funded, international prospective cohort study to examine social and psychological predictors of chronic post-surgical pain following cardiac surgery. His research focuses on remote automated monitoring and virtual recovery support for people recovering from cardiac and vascular surgery, decision support for people living with RFA, and global-scale, web-based dissemination of new evidence on persistent forms of cardiac pain.
Mike has been recognized for his research and advocacy by receiving the Canadian Pain Society Early Career Award and the McMaster University Arch Award for outstanding contributions to society; and was the first University Scholar (2019) from the McMaster School of Nursing.
Andrew Mente is a Principal Investigator for the Epidemiology program at PHRI, and Assistant Professor in the Department of Health Research Methods, Evidence, and Impact at McMaster University. He’s working in the ongoing Population Urban and Rural Epidemiological (PURE) study, interested in the role of essential minerals (sodium, potassium, calcium, magnesium) and dietary fatty acids in cardiovascular diseases in populations around the world.
He has received a Research Fellowship from the Heart and Stroke Foundation of Canada, and a Research Early Career Award from Hamilton Health Sciences, and has published more than 45 papers and two book chapters. Andrew received his doctoral degree in Epidemiology from the University of Toronto, and completed his post-doctoral training in cardiovascular epidemiology at McMaster University.
Kanjana (Sashi) Perera is a Scientist in the Brain Health and Stroke research program at PHRI, Assistant Professor, Medicine (neurology), McMaster University, and a stroke neurologist at Hamilton Health Sciences. Her main research focus is on secondary stroke prevention, cryptogenic stroke, and uncommon causes of stroke and the optimization of clinical care in this patient population.
She has served as Principal Investigator and Co-Investigator for Phase II and III clinical trials, and is on the adjudication committees for international multicenter stroke/cardiovascular trials. She has won research awards, and her work has been published in high-impact medical journals. She obtained her medical degree from Sri Lanka with Honors for academic excellence. She completed her training in Neurology at the University of Western Ontario in 2013 and subsequently pursued a fellowship in Stroke/Vascular Neurology at McMaster University.
Marie Pigeyre is a Scientist at PHRI, and Assistant Professor in the Division of Endocrinology, McMaster University. She has received peer-reviewed New Investigating Funding from Hamilton Health Sciences, and is supported by the Medicine Internal Career Award from McMaster University.
She completed her clinical and research post-doctoral fellowship in epidemiology, genetics and biomarkers at McMaster University in 2019, preceded by a PhD in Epidemiology and Genetics, medical degree, and endocrinology training at the University of Lille in France (2007).
Zubin Punthakee is an Associate Professor in the Departments of Medicine (endocrinology and metabolism) and Pediatrics, at McMaster University. His research interests are: clinical trials of diabetes management; association between obesity and insulin resistance/diabetes, especially in youth; health care delivery and outcomes during transition from pediatric to adult care; and long-term outcomes of pediatric endocrine diseases.
At PHRI, he has held leadership roles in the TIDE trial, ORIGINALE study and RICH LEGACY study. He has published more than 22 articles, been supported by Research Career Awards from Hamilton Health Sciences and the Department of Medicine at McMaster University, and holds research grants from agencies including the Canadian Institutes of Health Research.
Jason Roberts is a clinical cardiac electrophysiologist at Hamilton Health Sciences and an Associate Professor of Medicine at McMaster University. As a clinician researcher, Jason’s interests focus on the genetics of cardiac arrhythmias, and evaluating the clinical utility of new drugs and gene-based therapies as treatments for both rare and common forms of cardiac arrhythmias. Previously, he worked at the University of Western Ontario as part of the London Heart Rhythm Program, where his research focused on refining insights into the clinical and genetic features of inherited arrhythmia syndromes.
He completed his training in cardiac electrophysiology at the University of California, San Francisco (UCSF) and his cardiology fellowship at the University of Ottawa Heart Institute, during which he worked with Spartan Biosciences to develop the first point-of-care genetic test in clinical medicine (trial results published in The Lancet). He holds a Master’s degree in clinical epidemiology and biostatistics from UCSF.
JD Schwalm is a Principal Investigator in the Knowledge Translation and Health Systems research program at PHRI, an Associate Professor, Department of Medicine (cardiology) at McMaster University, and an interventional cardiologist at Hamilton Health Sciences. He has published more than 50 peer-reviewed scientific papers and book chapters.
He completed medical school, internal medicine residency, and cardiology fellowship training at McMaster University, Ontario, followed by an interventional cardiology fellowship at McMaster and further training in that field at the University of Ottawa Heart Institute. He is a fellow of the Royal College of Physicians and Surgeons of Canada, with certification in internal medicine and cardiology.
Mike Sharma, MD MSc FRCPC, is the Director of the Stroke Program at McMaster University and Hamilton Health Sciences and holds the Michael G DeGroote Chair in Stroke Prevention, at McMaster University in Hamilton, Canada. His research interests include the development of new antithrombotic treatments, incorporating magnetic resonance imaging endpoints into the design of stroke prevention trials and examining the effects of anticoagulants on stroke recurrence and covert brain infarcts.
He has led trials and sub-studies in large prevention trials focused on these areas including COMPASS MIND, NAVIGATE ESUS, DATAS II and currently leads as principal investigator, the global phase II AXIOMATIC-SSP trial investigating FXI inhibition for stroke prevention in 27 countries.
He has published more than 140 articles in referred journals, is the immediate past Chair of the Canadian Stroke Consortium, the professional organization for stroke physicians and clinical trialists in Canada and established the stroke program at the University of Ottawa. Dr. Sharma is committed to developing integrated processes for stroke care and developing human and system capacity for the next generation of stroke trials.
Tej Sheth is a Scientist with the Perioperative and Surgery research program at PHRI, as well as a Principal Investigator in atherosclerosis imaging, an Associate Professor in the Department of Medicine at McMaster University, and a interventional cardiologist at Hamilton Health Sciences. His research interests include invasive and non-invasive coronary imaging modalities, including coronary angiography, optical coherence tomography, and CT coronary angiography. He is Director of the CT Angiographic Core Lab for the COMPASS CABG study and the COMPLETE trial at PHRI.
Ashkan Shoamanesh is the founding Director, Hemorrhagic Stroke Research Program and Scientist, at PHRI, Assistant Professor of Medicine (Neurology), McMaster University, and Director, Stroke Fellowship Program at Hamilton Health Sciences and McMaster. He is the inaugural Marta and Owen Boris Chair in Stroke Research and Care at McMaster. His research is focused on improving the clinical care of patients with stroke or who are at risk for stroke resulting from blood vessel rupture and bleeding into the brain.He is the founding Chair of the Canadian Hemorrhagic Stroke Trials Initiative (CoHESIVE) and leads as principal investigator the global phase III ENRICH-AF trial investigating optimal stroke prevention in intracranial hemorrhage survivors with atrial fibrillation in 22 countries.
He has been awarded the most prestigious early career awards in stroke granted by the American Heart/Stroke Association (2015 Mordecai Y.T. Globus and 2019 Robert G. Siekert New Investigator Awards in Stroke), American Academy of Neurology (2020 Michael S. Pessin Stroke Leadership Prize), and Heart and Stroke Foundation of Canada (2019 Henry J.M. Barnett Scholarship – recognizing the highest ranked National New Investigator in cerebrovascular disease research), amongst other notable awards, including the 2019 International Stroke Conference Paul Dudley White International Scholar Award and the 2014 European Stroke Conference Young Investigator Award.
Harriette Van Spall
Harriette Van Spall
Harriette Van Spall is a Scientist for the Arrhythmia and Heart Failure research program and the Knowledge Translation and Health Systems program at PHRI, an Associate Professor, Department of Medicine (cardiology) at McMaster University. Her research, supported by CIHR and the Ministry of Health, is in quality of care and outcomes, knowledge translation, and health systems improvement pertaining to heart failure. She has won several research awards, and her work has been published in high-impact medical journals, including JAMA, Lancet, Circulation, and Annals of Internal Medicine.
She earned her Doctor of Medicine degree from the University of Toronto, and a Master of Public Health degree from the Harvard School of Public Health. She completed postgraduate training in Internal Medicine, Cardiology, and Echocardiography at the University of Toronto.
Michael Walsh is a Principal Investigator in the Renal research program at PHRI, and an Assistant Professor, Department of Medicine (nephrology), McMaster University. His research activities are in the areas of the treatment of patients who require dialysis, severe glomerular disease, and perioperative acute kidney injury. He has published more than 70 papers and two book chapters.
He holds a Kidney Research Scientist Core Education and National Training (KRESCENT) Program New Investigator award through CIHR and the Kidney Foundation of Canada. He’s received multiple Top Abstract awards from the Canadian Society of Nephrology, the Chalmers Prize from the Society for Clinical Trials, and the Detweiller Traveling Scholar Award from the College of Physicians and Surgeons of Canada.
Richard Whitlock is Associate Chair, Research, and a Professor at the Department of Surgery, McMaster University. He was awarded the inaugural Canada Research Chair in Cardiovascular Surgery in 2020.
As well as being a PHRI Scientist, Richard is a cardiac surgeon and intensive care physician at Hamilton Health Sciences. His clinical focus is on aortic valve intervention and aortic surgery. He is a lead investigator for the CIHR funded studies SIRS, LAAOS III, and TRICS III, which have established a network of more than 120 centres to address important questions in his field.
He has published more than 90 articles in referred journals. Medically qualified at the University of Toronto, Richard received his specialist training in cardiac surgery and critical care medicine at McMaster University. In 2012, he received his PhD in clinical epidemiology.
Jorge Wong is a cardiologist and cardiac electrophysiologist at Hamilton Health Sciences, as well as a scientist in the Arrhythmia and Heart Failure program at PHRI. His research interests focus primarily on the intersection between atrial fibrillation and heart failure, atrial fibrillation epidemiology and catheter ablation for atrial fibrillation. He holds research grants from the Heart and Stroke Foundation of Canada, the Canadian Cardiovascular Society, and Hamilton Health Sciences.
He obtained his MD at McMaster, followed by his internal medicine and cardiology training at the University of Western Ontario. Jorge subsequently completed his clinical electrophysiology fellowship at the University of Calgary and at the Brigham and Women’s Hospital in Boston. He has a Master of Public Health degree from the Harvard School of Public Health, and is currently pursuing his PhD in Health Research Methods at McMaster.
Matthew Lanktree is a clinical scientist in adult nephrology genetics who cares for patients with chronic and end-stage kidney disease at St. Joseph’s Healthcare Hamilton and Hamilton Health Sciences. He is an Assistant Professor, Department of Medicine (division of nephrology) and Department of Health Research, Methods, Evidence and Impact, at McMaster University. His research areas of interest are: nephrology genetics; cardiovascular disease in patients with chronic kidney disease; dialysis; and polycystic kidney disease.
He obtained a combined MD and PhD at Western University with research in human genetics before residency in internal medicine and nephrology at McMaster University. He then completed a post-doctoral research fellowship in heritable kidney disease at the University of Toronto before returning to McMaster as faculty in 2019. He has published more than 60 articles in high-impact journals in genetics and medicine, and has set his goal to translate genetic studies into improved care of patients with kidney disease.
Jessica Spence is a cardiac anesthesiologist and intensivist who completed a research fellowship at PHRI and a PhD in Clinical Epidemiology under the supervision of PJ Devereaux.
She is an Assistant Professor at McMaster University and the Principal Investigator of the B-Free Cluster Crossover Trial. Her research program focuses on the perioperative outcomes of cardiac surgery.
William McIntyre is an Assistant Professor (cardiology), Department of Medicine, McMaster University, a cardiologist at Hamilton Health Sciences, and an Investigator in the Arrhythmia and Heart Failure research program at PHRI. His research interests include atrial fibrillation – including screening, detection and cardioversion, cardiac devices and methods in randomized clinical trials.
He holds fellowship awards from CIHR and the Canadian Stroke Prevention Intervention Network (C-SPIN). He holds research grants from the Canadian Cardiovascular Society (CCS) Atrial Fibrillation Awards Program and the Heart and Stroke Foundation of Canada. William has published 150 peer-reviewed articles, and was the 2018 Recipient of the CCS Trainee Excellence in Education Award. He completed Medical School and Internal Medicine Residency at Queen’s University, and his adult cardiology residency at the University of Manitoba.