completed

The objective of the TIMACS study was to compare relative efficacy, safety, and cost effectiveness of a management strategy of coronary angiography and intervention performed within 24 hours of randomization versus delayed coronary angiography and intervention in patients after 36 hours with ACS.

Primary Endpoint

Adjudicated. Composite of death, myocardial (re-) infarction, or stroke. Secondary Points: Death/myocardial infarction (MI)/stroke/refractory ischemia/repeat intervention at discharge/30d/180d. Death/MI/stroke at discharge/30d/180d. Major bleeding at 30d. Each component of the primary outcome individually at discharge/30d/180d.

Study Type

Interventional - Procedure

Study Design

Randomized, single blind (outcomes assessor), parallel group

NO. of Countries

14

NO. of Sites

38

NO. of Participants

3031

Study Period

2003-2008

Sponsor

PHRI

Sanofi

Canadian Institutes of Health Research (CIHR)

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