completed

The PAIN-STOP pilot study assessed the feasibility of a larger randomized controlled trial evaluating NMDA antagonists and IV steroids, as compared to placebo, in decreasing the chances of clinically significant persistent post-surgical pain (PPSP) after video assisted thoracoscopic surgeries (VATS).

Patients were recruited at two centres over five months, and followed for three months post-surgery.

Primary endpoint:

The proportion of:

1) eligible patients recruited;

2) patients adhering to the study protocol; and

3) patients completing the follow-up at three months.

Along with PHRI’s PJ Devereaux, the co-Principal Investigator of the PAIN-STOP study was Harsha Shanthanna, Associate Professor, Anesthesia, McMaster University.

Study Type

Interventional - Procedure

Study Design

Multi-centre, blinded, randomized controlled trial with 2 X 2 factorial design

NO. of Countries

1

NO. of Sites

1

NO. of Participants

48

Study Period

2017

Sponsor

PHRI

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