The NeuroVISION Study will characterize the incidence, impact, and risk factors of covert stroke in adults undergoing noncardiac surgery. We will determine the incidence of acute covert stroke using an MRI study of the brain in the days following noncardiac surgery, and will characterize the epidemiology and the impact of covert stroke in patients undergoing noncardiac surgery.

Primary endpoint:

  • Postoperative cognitive dysfunction

Secondary endpoints:

  • Incidence of covert stroke
  • Postoperative delirium
  • Physical function
  • Quality of life
  • Depressive symptoms
  • Clinical outcomes.

The Co-Principal Investigator on the NeuroVISION study was Marko Mrkobrada, Assistant Professor, Robarts Research Institute, University of Western Ontario

Study Type


Study Design

Prospective cohort evaluation

NO. of Countries


NO. of Sites


NO. of Participants


Study Period

2014 - 2018



Canadian Institutes of Health Research (CIHR)

Auckland District Health Board Charitable Trust

Neurological Foundation of New Zealand

Health and Medical Research Fund

Food and Health Bureau, Government of the Hong Kong Special Administration Region, China

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