Abdominal aortic aneurysms (AAA) are frequent in older population and if left untreated, are at increased risk of life-threatening rupture.
Endovascular aneurysm repair (EVAR) is a minimally-invasive procedure often performed as an alternative to open surgical repair.
EVAR is associated with less postoperative complications, and patients are frequently discharged in the first 24 hours after the intervention. However, EVAR is not associated with a long-term mortality advantage over open repair.
Early cardiac complications occurring after patient discharge that may be undetected might explain the long-term prognostic difference.
The EVAR study was a multicenter prospective cohort study which assessed major cardiovascular complications in patients undergoing EVAR.
Patients will have troponins measured in the first three postoperative days and will be followed for 30 days post-surgery.
For the pilot phase, the primary objective was to determine the feasibility of obtaining at least one troponin (Tn) measurement at day 2 or day 3 after surgery in more than or equal to 75 percent of enrolled patients, whether they are home or in the hospital.
Multicentre prospective cohort
PJ Devereaux is Senior Scientific Lead, Perioperative and Surgery, PHRI, Professor and University Scholar in the Departments of Health Research Methods, Evidence, and Impact (HEI) and Medicine at McMaster University, and Director of the Division of Cardiology at McMaster.
The focus of his clinic research is vascular complications around the time of surgery, leading several large, international RCTs and observational studies addressing this issue. He has published more than 250 peer-reviewed papers and more than 50 book chapters and editorials. He is supported by a Tier 1 Canadian Research Chair in Perioperative Medicine, and holds the Yusuf Chair in Cardiology at McMaster University.
Jessica Vincent has more than 15 years’ experience in coordinating and managing large, international clinical trials. As Associate Program Manager, she oversees interventional trials, registries, and observational research studies in the areas of perioperative medicine, cardiac surgery, and digital health.
She holds an Honours Bachelor of Science Degree from Queens University, and a Master of Clinical Epidemiology Degree from the University of Newcastle.
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