The DANCE Pilot trial will compare the safety of direct oral anticoagulants (DOAC) versus warfarin in the early period (30 days) after cardiac surgery in patients with an indication for oral anticoagulation.

The objective of this trial is to determine the feasibility of conducting a larger trial.

The SUNDANCE trial – which is a sub-study of the DANCE trial – focuses on subclinical valve thrombosis in patients with bioprosthetic aortic valve replacement.

DANCE and SUNDANCE substudy - Download PDF
Study Type

Interventional - Drug

Study Design

Multi-centre, open randomized controlled trial

NO. of Countries


NO. of Sites


NO. of Participants


Study Period

2021 - 2023



Canadian Cardiovascular Society

Early Career Arrhythmia and Atrial Fibrillation Award (ECA3)

McMaster Surgical Associates

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