Study Type
Interventional - Procedure
The findings of the COMPLETE trial received 1A Recommendation & Evidence in the 2021 ACC/AHA/SCAI Guideline for Coronary Artery Revascularization.
COMPLETE determined that, on a background of optimal medical therapy with low dose ASA and ticagrelor, a strategy of multi-vessel revascularization, involving staged PCI using drug eluting stents of all suitable non-infarct related artery lesions, was superior to a strategy of culprit lesion-only revascularization in reducing the composite outcome of cardiovascular (CV) death or new MI in patients with multi-vessel disease who have undergone successful culprit lesion primary PCI for STEMI.
Key secondary objectives were:
COMPLETE Long-Term Follow Up
In an observational registry, up to 1500 consenting COMPLETE study participants (at a planned 55 sites in 3 countries) will be followed passively for five to 10 years. During this period, there will be no protocol-mandated therapies, and the primary care physicians will determine treatment of all study participants based on their interpretation of the available evidence.
The COMPLETE Follow-up study is focused on identifying the occurrence of deaths and major CV events and, if possible, linkages to administrative national or regional databases that record mortality and major morbidity (e.g. hospitalizations for myocardial infraction or stroke) will be conducted.
COMPLETE - Download PDF COMPLETE OCT - Download PDF COMPLETE Timing - Download PDFInterventional - Procedure
Randomized, prospective, multicenter, open label trial
31
140
4041
2013-2019
PHRI
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