completed

Cardiac, vascular, and cognitive dysfunction have a strong impact on the quality of life, longevity and health care costs, in Canada and globally. It is of paramount importance to understand the early determinants of such dysfunction and its progression to clinical events, especially given the increasing prevalence of known cardiovascular (CV) risk factors, which result in organ dysfunction including atrial fibrillation, congestive heart failure and dementia, threatening the financial sustainability of health care systems.

The objectives of the Alliance are:

  • To understand the role of socio-environmental and health system contextual factors (societal structure, built environment, nutrition environment, tobacco environment, access to and quality of health services) on individual CV risk factors, subclinical vascular disease, and clinical CV events.
  • To identify early markers for sub-clinical dysfunction in the brain, heart and abdomen using magnetic resonance imaging, and to investigate the contextual and individual level determinants (i.e. biologic factors such as genetic and molecular signatures) of this dysfunction, as well as to assess the predictive value of sub-clinical dysfunction on the development of clinical CV events.

Research activities in the Canadian Alliance for Healthy Hearts and Minds have included the CAHHM: First Nations cohort study; and the CAHHM: Chinese-Canadian cohort study.

The CAHHM was led by co-Principal Investigators: Sonia Anand of PHRI; Matthew Friedrich of Montreal Heart Institute; and the late Jack Tu until his demise in 2018.

Study Type

Observational

Study Design

Observational cohort

NO. of Countries

1

NO. of Sites

27

NO. of Participants

9700

Study Period

2013-2019

Sponsor

PHRI

VIDEO: OVERVIEW OF CAHHM

VIDEO: WHERE YOU LIVE, A CAHHM SUBSTUDY

VIDEO: CAHHM FIRST NATIONS COHORT WORKSHOP

Alberta Tomorrow Project

Atlantic PATH

Canadian Longitudinal Study on Aging

CARTaGENE

Montreal Heart Institute Biobank

Ontario Health Study

Prospective Urban and Rural Epidemiology (PURE) study

2,000 Reserve-based Indigenous peoples from across Canada who are a high-risk group for CVD and cancer

Back To Top