The research question for the C-CUSP ED study was: Does a multidisciplinary emergency department (ED)-based intervention, using patient educational materials and prescription of novel oral anticoagulant (NOAC) with immediate follow-up by a community-based clinic dedicated to the care of atrial fibrillation (AF), improve emergency physician prescription of new NOAC for patients presenting to the emergency department with AF?

Primary endpoint:

The rate of new oral anticoagulant (OAC) prescriptions at  emergency department discharge in patients with atrial fibrillation who are OAC eligible but were not on OAC at ED presentation.

Ratika Parkash, of the Nova Scotia Health Authority, was a co-Principal Investigator on the C-CUSP ED

Study Type

Interventional - Procedure

Study Design

Multicentre pragmatic 3-phase implementation

NO. of Countries


NO. of Sites


NO. of Participants


Study Period

2015 - 2017



Canadian Stroke Prevention Intervention Network (C-SPIN)

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