Study Type
Interventional - Procedure
For more information, email: brave@phri.ca
BRAVE is testing bariatric surgery, versus medical weight management, in severely obese patients (BMI 35 or higher) who have cardiovascular disease including heart failure.
Bariatric surgery is expected expected to reduce weight by 40 kg. on average.
Primary outcome will be major CV events, including HF at 5 years.
In a subset of 200 individuals, we will test its’ impact on cardiac structure and function by echocardiography.
This trial will establish whether weight reduction in obese individuals can reduce HF development or progression.
BRAVE US collaborators with Salim Yusuf at Toronto investigators meeting, Jan. 28, 2023
Interventional - Procedure
Open-label, parallel-arm RCT
6
50
2000
2021 - 2027
PHRI
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