The objective of the AF-HTN Pilot study was to compare current guideline-based treatment of blood pressure (target less than or equal to 140/90) to an aggressive treatment of blood pressure (target less than or equal to 120/80) for the prevention of stroke in atrial fibrillation (AF) patients.

Patients with AF who have high blood pressure, from four clinical centres across Canada, were invited to participate in the study.

Patients were assigned to either usual care (blood pressure treated to the current guideline-based target of less than 140/90) or aggressive treatment (blood pressure treated to a level of less than 120/80), and had five visits during six months to achieve this target.

The outcome of this pilot phase was to determine the actual achieved blood pressure at 6 and 12 months in the two treatment groups, the difference in blood pressure between groups, the rate of adverse events (if any) in both groups and the feasibility of recruiting eligible study patients.

Study Type

Interventional - Drug

Study Design

Cohort study

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