OCEANIC-STROKE: Antithrombotic Therapy for Noncardioembolic Ischemic Stroke: Current Evidence and Future Directions
Stroke
Brett Cucchiara; Jean M Connors; Alejandro A Rabinstein; Mukul Sharma
March 2026
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RADICAL-PC: Androgen deprivation therapy and kidney function in patients with prostate cancer: an analysis of the RADICAL-PC cohort.
International Urology and Nephrology
Geethan Baskaran; Jehonathan H Pinthus; Sarah Karampatos; Kelvin K H Ng; Cristina Cano Garcia; Rajibul Mian; Lonnie Pyne; Scott Brimble; Laurence H Klotz; Vincent Fradet; Joseph B Selvanayagam; Avirup Guha; Celestia S Higano; Álvaro Avezum; Ludhmila A Hajjar; Germano Dallegrave Cavalli; Felipe H Valle; Emmanuelle Duceppe; Cesar D O L Dusilek; Bobby Shayegan; Rafaela Kirchner Piccoli; Juan Gomez-Mesa; Tamim Niazi; Margot K Davis; Jose E Cita Pardo; Patrick P Luke; Darryl Leong; & RADICAL-PC Investigators
March 2026
CANPWR: Longitudinal Improvements in Health-Related Quality of Life Among Children Enrolled in the CANadian Paediatric Weight Management Registry Over 3 Years.
Pediatric OBESITY
Marina Ybarra; Grace Rebekah; Geoff D C Ball; Annick Buchholz; Jill Hamilton; Josephine Ho; Ian Zenlea; Rajibul Mian; Lehana Thabane; Katherine M Morrison
March 2026
PURE-China: The interplay between antihypertensive medication and lifestyle with cardiovascular outcomes in patients with hypertension
EPMA Journal
Biyan Wang; Zhiguang Liu; Tong Bu; Sumathy Rangarajan; Qiuyan Ma; Xiaocong Li; Qi Qiu; Yang Lin; Lap Ah Tse; Bo Hu; Salim Yusuf; Qiujing Cai; Wei Li; PURE-China Investigators
March 2026
PURE: Association Between Ultraprocessed Food Intake and Inflammatory Bowel Disease Risk: A Propensity-Matched Analysis With Monte Carlo Simulation From the Prospective Urban Rural Epidemiology Study.
Gastroenterology
Neeraj Narula; Emily C L Wong; Sumathy Rangarajan; Victoria Miller; Paul Moayyedi; Salim Yusuf; PURE Investigators
March 2026
CANPWR: Residential Neighbourhood Environments and Health Behaviours Among Children and Adolescents Initiating Obesity Management Care: Secondary Analyses of Data From the CANadian Paediatric Weight Management Registry
Pediatric OBESITY
Tang Y, Semenic S, Baillot A, Riva M, Ball GDC, Hadjiyannakis S, Hamilton J, Ho J, Legault L, Zenlea I, Morrison KM, Van Hulst A.
February 2026
ARCADIA: Apixaban Versus Aspirin and Risk of Hemorrhage
Annals of Neurology
Kamel H, Longstreth WT Jr, Tirschwell DL, Kronmal RA, Elkind MSV, Pauls Q, Garcia RA, Plummer P, Sabagha N, Ammar A, Healey JS, Shoamanesh A, Sheth KN, Broderick JP, Navi BB; ARCADIA Investigators
February 2026
VISION Cardiac Surgery: High-Sensitivity Cardiac Troponin I and Mortality Following Off-Pump and On-Pump Coronary Artery Bypass Surgery: A Secondary Analysis of the trial
Interdisciplinary CardioVascular and Thoracic Surgery
Lee GS, Tam DY, Vervoort D, Lee SF, Brady K, Belley-Cote E, Devereaux PJ, Lamy A, Whitlock R, Louie R, Fremes SE.
February 2026
IMAGINE: Patient-reported Symptoms Are Independent of Extent of Disease in Longstanding Ulcerative Colitis. Magic in Imagine
Journal of Clinical Gastroenterology
Bernstein CN, Nugent Z, Panaccione R, Marshall DA, Kaplan GG, Vanner S, Dieleman LA, Graff LA, Otley A, Jones J, Buresi M, Murthy S, Borgaonkar M, Bressler B, Bitton A, Croitoru K, Sidani S, Fernandes A, Moayyedi P
January 2026
COMPASS: Net Clinical Benefit of Extended Dual Pathway Inhibition in Chronic Coronary Syndrome as Classified by the 2024 ESC Criteria: a COMPASS Substudy
European Heart Journal – Cardiovascular Pharmacotherapy
Würtz M, Olesen KKW, Yi Q, Eikelboom JW, Maeng M.
January 2026
STAR-T: Randomized, Sham-Controlled Trial of Intraoperative Ticagrelor Removal to Reduce Perioperative Bleeding
The Journal of Thoracic and Cardiovascular Surgery
Mack MJ, Whitlock R, Chu MWA, Taylor B, Zias EA, Liu D, Protos AN, Rokkas C, Pelletier M, Choi D CW, Saha T, Sellke FW, Schneider DJ, Thourani VH, Douketis J, Mazer CD, Fan W, Deliargyris EN, Gibson CM; STAR-T Investigators.
January 2026
HIP ATTACK: Cemented Fixation in Arthroplasty for Hip Fractures Does Not Increase Cardiopulmonary Complications: A Secondary Analysis of the HIP ATTACK Trial
Clinical Orthopaedics and Related Research
Righolt CH, Borges FK, Sniderman J, Turgeon TR, Devereaux PJ, Bhandari M, Guerra Farfan E, Lawendy AR, Patel A, Tandon V, Szczeklik W, Ofori S, Harvey V, Bohm ER, Wood GCA; on behalf of the HIP ATTACK Investigators
January 2026
OCEANIC-STROKE: Rationale, design and baseline characteristics of participants in the OCEANIC-STROKE trial of FXIa inhibition for secondary stroke prevention
European Stroke Journal
Mukul Sharma, Qiang Dong, Teruyuki Hirano, Scott E Kasner, Jeffrey Saver, Jaime Masjuan, Andrew M Demchuk, Charlotte Cordonnier, Daniel Bereczki, Georgios Tsivgoulis, Roland Veltkamp, Ivan Staikov, Hee-Joon Bae, Bruce C V Campbell, Andrea Zini, I-Hui Lee, Sebastian Ameriso, Martin Kovar, Robert Mikulik, Robin Lemmens, José M Ferro, Thompson Robinson, Hanne Christensen, Serefnur Ozturk , Ronen R Leker , Peter Turcani , Agnieszka Slowik , Pablo Amaya , Fan Kee Hoo , Gian Marco De Marchis , Michael Knoflach , Pillai N Sylaja , Jukka Putaala , Jonathan M Coutinho , H Bart van der Worp , Evija Miglane , Vaidas Matijosaitis , Arne G Lindgren , Gisele Sampaio Silva , Else Charlotte Sandset , Saule Tleubergenovna Turuspekova , Raed A Joundi , Karleen Schulze , Olga Shestakovska , Jennifer Gilbride , Shrikant I Bangdiwala , Lizhen Xu , Eva Muehlhofer , Pablo Colorado , Hardi Mundl , Lars Keller , Ashkan Shoamanesh OCEANIC-STROKE Investigators
January 2026
ORIGIN, REWIND: Prediction of heart failure as the first major cardiovascular disease event in type 2 diabetes
Diabetes, Obesity and Metabolism
Sacre JW, Lundegard K, Mohammedi K, Carstensen B, Gerstein HC, Shaw JE.
January 2026
HD PCI: Design and rationale of the HD PCI trial: A cluster randomized crossover trial of higher vs. lower dose heparin for elective percutaneous coronary intervention
American Heart Journal
d'Entremont MA, Lee SF, Wijeysundera HC, Tsang MB, Amlani S, Wassef A, Lavi S, So DYF, Betz J, Tyrwhitt J, Graham J, Cantor WJ, Bagherli A, Vijayaraghavan R, Jolly SS.
December 2025
