Ongoing Perioperative and Cardiac Surgery Research

The DANCE trial is an international, multicentre randomized controlled study that examines the safest oral anticoagulation strategy for patients who require blood thinners in the first 30 days after cardiac surgery. The trial compares direct oral anticoagulants (DOACs) with vitamin K antagonists, focusing on major bleeding and other key cardiovascular outcomes to help inform perioperative care and improve patient safety.

The SAFE trial is an international randomized clinical study evaluating whether concomitant surgical ablation of atrial fibrillation during cardiac surgery improves patient outcomes. The trial focuses on safety‑driven interventions during surgery and early postoperative care, with the goal of reducing complications such as heart‑failure–related hospital readmissions and informing evidence‑based surgical practice.