We’re looking for a Principal Biostatistician to join our Biostatistics team at the Population Health Research Institute. This is a great opportunity to apply your expertise and make a meaningful impact in health research.
The Principal Biostatistician will be responsible for the development of new statistical methods and the design of computer programs to perform statistical analyses. They will also be responsible for the application of complex statistical and technical skills toward the collection, analysis, and translation of statistical data for a variety of research projects. This role serves as an expert statistical consultant for clinical projects and acts as the Project Lead Statistician and/or the sole representative for Biostatisticians, Real-World Data Scientists, Patient-Centered Outcomes Research Scientists, statistical programmers, and clinical data managers on a Global Development Team. They will also act as the Biostatistics Lead for Health Authority interactions.
As a Principal Biostatistician you will:
- Develop new statistical methods and strategies to cope with the absence or failure of existing mathematical procedures.
- Design and write computer programs to perform statistical analyses.
- Prepare and present reports to the external Data and Safety Monitoring Board (DSMB) overseeing a randomized controlled trial.
- Lead cross-functional teams in overseeing the generation of health authority submission datasets and associated documentation.
- Oversee the deliverables from external CROs.
- Provide analytical and strategic leadership for exploratory activities, such as personalized healthcare, biomarker development and PK/PD modelling.
- Accountable for the statistical integrity, adequacy, and accuracy of non-clinical studies.
- Develop estimates of time and resources for various projects.
- Apply established statistical methods and techniques to analyze and interpret data.
- Identify the appropriate method of statistical analysis and apply statistical techniques to interpret data.
- Compile and analyze data and interpret trends, fluctuations, and other changes that may emerge.
- Develop forms and procedures required for the collection and compilation of data.
- Devise and implement administrative procedures for the collection of data.
- Oversee the design and maintenance of databases, data collection forms, error checking methods, and related programs for collection, analysis, and reporting.
- Design database specifications and modify existing software packages to meet specific research project needs.
- Document new designs, codes, and modifications.
- Develop test cases and test system upgrades and enhancements.
- Write sections of scientific papers, funding proposals, grants, and abstracts.
- Identify and resolve database and software problems.
- Conduct data audits, compile results, analyze and summarize audit findings.
- Coordinate and manage the collection, delivery, entry, verification, analysis, and reporting of data.
- Provide advice regarding data collection and analysis required for research projects.
- Recommend modifications to processes related to data collection and data entry conventions and develop implementation plans.
- Apply specialized knowledge and scientific principles to review, critically appraise and interpret published literature.
- Research pertinent literature in a designed project area and analyze the applicability of the concepts.
- Review case report forms, determine possible protocol deviations, discrepant data, and inconsistent reporting.
- Facilitate meetings and prepare recommendations on statistical and reporting strategies.
- Exchange information with colleagues and statistical experts.
- Explain statistical approaches to others who do not have the equivalent knowledge in statistical methods.
- Develop and deliver presentations and training sessions.
- Safeguard the confidentiality of study data.
Qualifications include:
- Doctoral degree in a relevant field of study.
- Requires 2 years of relevant experience.
This is a McMaster University temporary (12.2 months) posting: 35 hours/week Monday through Friday, based in Hamilton, Ontario.
For more information - and to apply - go to: Job Number 67896
Deadline for applications: March 12, 2025, 11:59 pm ET.
