Our Story - About Us

Since humble roots in 1993 in Hamilton, Canada, PHRI has grown both the scope of our studies and reach of participants – such that today, we conduct research in 102 countries on six continents, with 1,500,000 people involved in up to 100 studies. In 1999, Dr. Salim Yusuf’s original cardiology research group was formally established as The Population Health Research Institute (PHRI), jointly supported by McMaster University and Hamilton Health Sciences.

Originally focused on cardiovascular disease and diabetes, PHRI’s research areas have broadened to include brain health, perioperative and surgery, stroke, thrombosis, renal, the environment and health, obesity, GI, health systems, and more. PHRI is a world leader in large clinical trials, population health studies, and epidemiology expertise, with the capacity to conduct several international studies concurrently, tens of thousands of participants in each study.

Global collaboration is a strong attribute of PHRI as revealed by our esteemed international fellows, our multi-disciplinary teams of world-class scientists, our mentorship, and a “family” of research institutes around the world we call PHRI International.

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PHRI is known around the world for tackling global health challenges. Trials from the 1990s such as HOPE and INTERHEART, to more recent trials like COMPASS, COMPLETE and MANAGE, and epidemiological studies such as the globe-spanning observational study, PURE, now nearing the end of its 20-year run.

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The Story of PHRI

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PHRI papers in 2020

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Papers with >1000 citations

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Regulatory approvals based on PHRI trials

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