The Population Health Research Institute (PHRI), jointly supported by McMaster University and Hamilton Health Sciences, is a world leader in large clinical trials, population health studies, and epidemiology expertise.

Since humble roots in 1993 in  Hamilton, Canada, PHRI has grown both the scope of our studies and reach of participant – such that today, we conduct research in 102 countries on six continents, with 1500000 million people involved in up to 100 studies.

Originally focused on cardiovascular disease and diabetes, PHRI’s research areas have broadened to include brain health, perioperative and surgery, stroke, thrombosis, renal, the environment and health, obesity, GI, health systems, and more.

Examining biological and genetic determinants of health, as well as social, environmental and policy factors, PHRI focuses on the prevention of cardiovascular disease, diabetes and other common conditions. Our capacity to conduct several international studies concurrently, with tens of thousands of participants in each study, is one that few organizations in the world can match.

A core strength of the PHRI is our multidisciplinary team of world-class scientists and research support teams. Our environment promotes collaboration and innovation, with a multifaceted approach which allows researchers to capitalize on the wealth of collective knowledge as they each bring areas of expertise to a single study.


PHRI papers in 2019


Papers with >1000 citations


Regulatory approvals based on PHRI trials