Recent Publications

VISION Cardiac Surgery: High-sensitivity troponin I after cardiac surgery and 30-day mortality

New England Journal of Medicine

PJ Devereaux, A Lamy, MTV Chan, RV Allard, VV Lomivorotov, G Landoni, H Zheng, D Paparella, MH McGillion, EP Belley-Cote, JL Parlow, MJ Underwood, CY Wang, N Dvirnik, M Abubakirov, E Fominskiy, S Choi, S Fremes, F Monaco, G Urrutia, M Maestre, LA Hajjar, GS Hillis, NL Mills, V Margari, JD Mills, JS Billing, E Methangkool, CA Polanczyk, R Sant'Anna, D Shukevich, D Conen, PA Kavsak, MJ McQueen, K Brady, J Spence, Y Le Manach, R Mian, SF Lee, SI Bangdiwala, S Hussain, FK Borges, S Pettit, J Vincent, GH Guyatt, S Yusuf, JS Alpert, HD White, RP Whitlock

March 2022

Association of clonal hematopoiesis of indeterminate potential with worse kidney function and anemia in two cohorts of patients with advanced chronic kidney disease

Journal of the American Society of Nephrology

C Vlasschaert, A McNaughton, M Chong, E Cook, W Hopman, B Kestenbaum, C Robinson-Cohen, J Garland, S Moran, G Paré, C Clase, M Tang, A Levin, R Holden, M Rauh, M Lanktree

February 2022

Caffeine blocks SREBP2-induced hepatic PCSK9 expression to enhance LDLR-mediated cholesterol clearance

Nature Communications

PF Lebeau, JH Byun, K Platko, P Saliba, M Sguazzin, ME MacDonald, G Paré, GR Steinberg, LJ Janssen, SA Igdoura, MA Tarnopolsky, SRW Chen, NG Seidah, J Magolan, RC. Austin

February 2022

PURE: Differences and agreement between two portable hand-held spirometers across diverse community-based populations

PLOS Global Public Health

M Duong, S Rangarajan, M Zaman, NM Nasir, P Seron, K Yeates, AM Yusufali, R Khatib, LA Tse, C Wang, A Wielgosz, K Teo, R Kumar, A Avezum, R Ismail, B Tumerdem, S Gopakumar, O Rahman, K Zatonska, A Rosengren, J Otero, R Kelishadi, R Diaz, T Puoane, S Yusuf

February 2022

NAVIGATE ESUS: Functional abilities of an international post-stroke population – Standard Assessment of Global Everyday Activities (SAGEA) scale

Journal of Stroke and Cerebrovascular Diseases

J Bosch, LA Pearce, M Sharma, R Mikulik, WN Whiteley, M Canavan, RG Hart, MJ O'Donnell

February 2022

CAHHM, PURE-Mind: Evaluation of adiposity and cognitive function in adults

JAMA Network Open

SS Anand, MG Friedrich, DS Lee, P Awadalla, JP Despres, D Desai, RJ de Souza, T Dummer, G Parraga, E Larose, SA Lear, KK Teo, P Poirier, KM Schulze, D Szczesniak, JC Tardif, J Vena, K Zatonska, S Yusuf, EE Smith

February 2022

VERDICT: Continuous noninvasive remote automated blood pressure monitoring with novel wearable technology – apreliminary validation study

JMIR mHealth and uHealth

MH McGillion, N Dvirnik, S Yang, E Belley-Cote, A Lamy, R Whitlock, M Marcucci, FK Borges, E Duceppe, C Ouellette, M Bird, SL Carroll, D Conen, JE Tarride, P Harsha, T Scott, A Good, K Gregus, K Sanchez, P Benoit, J Owen, V Harvey, E Peter, J Petch, J Vincent, M Graham, PJ Devereaux

February 2022

POISE-3: Rationale and design of the PeriOperative ISchemic Evaluation randomized controlled trial evaluating tranexamic acid and a strategy to minimize hypotension in noncardiac surgery

BMC Trials

M Marcucci, TW Painter, D Conen, K Leslie, VV Lomivorotov, D Sessler, MTV Chan, FK Borges, MJ Martinez Zapata, CY Wang, D Xavier, SN Ofori, G Landoni, S Efremov, YV Kleinlugtenbelt, W Szczeklik, D Schmartz, AX Garg, TG Short, M Wittmann, CS Meyhoff, M Amir, D Torres, A Patel, E Duceppe, K Ruetzler, JL Parlow, V Tandon, MK Wang, E Fleischmann, CA Polanczyk, R Jayaram, SV Astrakov, M Rao, T VanHelder, WKK Wu, CC Cheong, S Ayad, M Abusbakirov, M Kirov, K Bhatt, M de Nadal, V Likhvantsev, PP Iglesisas, HJ Aguado, M McGillion, A Lamy, RP Whitlock, P Roshanov, D Stillo, I Copland, J Vincent, K Balasubramanian, SI Bangdiwala, B Biccard, A Kurz, S Srinathan, S Petit, J Eikelboom, T Richards, PL Gross, P Alfonsi, G Guyatt, E Belley-Cote, J Spence, W McIntyre, S Yusuf, PJ Devereaux

January 2022

PURE: Variations in the financial impact of the COVID-19 pandemic across 5 continents – a cross-sectional, individual level analysis

The Lancet eClinical l Medicine

AK Khetan, S Yusuf, P Lopez-Jaramillo, A Szuba, A Orlandini, N Mat-Nasir, A Oguz, R Gupta, A Avezum, I Rosnah, P Poirer, KK Teo, A Wielgosz, SA Lear, LM Palileo-Villaneuva, P Seron, J Chifamba, S Rangarajan, M Mushtaha, D Mohan, K Yeates, M McKee, PK Mony, M Walli-Attaei, H Khansaheb, A Rosengren, KF Alhabib, IM Kruger, MJ Paucar, E Mirrakhimov, B Assembekov, DP Leong

January 2022

REWIND: HbA1c reduction in dulaglutide-treated patients irrespective of duration of diabetes, microvascular disease and BMI – a post-hoc analysis

ADA Diabetes Care

AYM Kwan, HC Gerstein, J Basile, D Xavier, JM Maldonado, S Raha, M Konig

January 2022

ACCORD: Advanced glycation end products predict loss of renal function and high-risk chronic kidney disease in type 2 diabetes

ADA Diabetes Care

J Koska, HC Gerstein, PJ Beisswenger, PD Reaven

January 2022

ONTARGET, TRANSCEND: Association between exercise frequency with renal and cardiovascular outcomes in diabetic and non-diabetic individuals at high cardiovascular risk

Cardiovascular Diabetology

M Bohm, H Schumacher, C Werner, KK Teo, EM Lonn, F Mahfoud, T Speer, G Mancia, J Redon, RE Schmider, K Sliwa, N Marx, MA Weber, U Laufs, B Williams, S Yusuf, JFE Mann

January 2022

ASSERT: Estimated incidence of previously undetected atrial fibrillation on a 14-day continuous electrocardiographic monitor and associated risk of stroke

EP Europace

WF McIntyre, J Wang, AP Benz, L Johnson, SJ Connolly, IC Van Gelder, RD Lopes, MR Gold, SH Hohnloser, CP Lau, CW Israel, JA Wong, D Conen, JS Healey

January 2022

PURE, INTERHEART, INTERSTROKE: Variations in risks from smoking between high-income, middle-income, and low-income countries: an analysis of data from 179 000 participants from 63 countries

The Lancet Global Health

S Thirunavukkarasu, KK Teo, P Britz-McKibbin, B Gill, S Islam, G Pare, S Rangarajan, M Duong, F Lanas, P Lopez-Jaramillo, PK Mony, Lakshmi Pinnaka, VR Kutty, A Orlandini, A Avezum, A Wielgosz, P Poirier, KF Alhabib, A Temizhan, J Chifamba, K Yeates, IM Kruger, R Khatib, R Yusuf, A Rosengren, K Zatonska, R Iqbal, W Lui, X Lang, S Li, B Hu, AL Dans, AH Yusufali, A Bahonar, MJ O'Donnell, M McKee, S Yusuf

January 2022

PURE: Developing indicators of age-friendly neighbourhood environments for urban and rural communities across 20 low-, middle-, and high-income countries

BMC Public Health

EJ Rugel, CK Chow, DJ Corsi, P Hystad, S Rangarajan, S Yusuf, SA Lear

January 2022

New England Journal of Medicine

Journal of the American Society of Nephrology

Nature Communications

PLOS Global Public Health

Journal of Stroke and Cerebrovascular Diseases

JAMA Network Open

JMIR mHealth and uHealth

BMC Trials

The Lancet eClinical l Medicine

ADA Diabetes Care

ADA Diabetes Care

Cardiovascular Diabetology

EP Europace

The Lancet Global Health

BMC Public Health

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