Prospective Urban and Rural Epidemiological Study
To examine the impact of urbanization on the development of primordial risk factors (for example: physical activity and nutrition changes), primary risk factors (for example: obesity, hypertension, dysglycemia and dyslipidemia, smoking), and CVD.
Adjudicated locally within each country. Each country will follow a similar protocol decided by the adjudicating committee.
Number of Patients
Number of Sites
Number of Countries
Sumathy Rangarajan, Gayle Lewis
Pam Mackie, SiuLim Chin, Shameena Ramacham
- PURE Concept Paper, Int J Epidemiol. 2009 Mar 4: Environmental and societal influences acting on cardiovascular risk factors and disease at a population level: a review. Chow CK, Lock K, Teo K, Subramanian S, McKee M, Yusuf S
- PURE Design Paper, Am Heart J. 2009 Jul;158(1):1-7.e1: The Prospective Urban Rural Epidemiology (PURE) study: examining the impact of societal influences on chronic non-communicable diseases in low-, middle-, and high-income countries. Teo K, Chow CK, Vaz M, Rangarajan S, Yusuf S; PURE Investigators-Writing Group
- EPOCH Pilot paper – PLoS One. 2010 Dec 10;5(12):e14294
- EPOCH Pilot – Cigarette pack labelling in 12 countries at different levels of economic development: J Public Health Policy. 2011 May;32(2):146-64