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EVAR

Official Title

Major Cardiovascular complications in patients undergoing EndVascular Aneurysm Repair

Status

Ongoing

Overview

Abdominal aortic aneurysms (AAA) are frequent in older population and if left untreated, are at increased risk of life-threatening rupture. Endovascular aneurysm repair (EVAR) is a minimally-invasive procedure often performed as an alternative to open surgical repair. EVAR is associated with less postoperative complications, and patients are frequently discharged in the first 24 hours after the intervention. However, EVAR is not associated with a long-term mortality advantage over open repair. Early cardiac complications occurring after patient discharge that may be undetected might explain the long-term prognostic difference. The EVAR Study is a multicenter prospective cohort study which will assess major cardiovascular complications in patients undergoing EVAR. Patients will have troponins measured in the first 3 postoperative days and will be followed for 30 days post-surgery.

Study Design

Multicentre prospective cohort study

Primary Endpoint

For the pilot phase: the primary objective is to determine the feasibility of obtaining at least one troponin (Tn) measurement at day 2 or day 3 after surgery in ≥ 75% of enrolled patients whether they are home or in the hospital.

Number of Patients

300

Number of Sites

7

Number of Countries

1

Study Period

2016-2019

Principal Investigator

P.J. Devereaux

Program Manager

Shirley Pettit

Research Coordinator

Jessica Vincent