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PROTECT-HF

Official Title

Prevalence of Subclinical Atrial Fibrillation in High Risk Heart Failure Patients and its Temporal Relationship with Hospital Readmission for Heart Failure

Status

Ongoing

Overview

In patients discharged from hospital after an admission for acute heart failure (HF) decompensation, subclinical atrial fibrillation (AF) of 30 minutes or greater in duration is common (at least 15% of patients without prior AF) and is associated with increased risk of re-hospitalization within 30-days. This is a multicentre, prospective cohort study in patients with a history of HF admitted to hospital with acutely decompensated HF. Eligible and consenting patients will be enrolled at 3 Hamilton area hospitals and receive 28-day ECG monitoring using a recording device applied to the patient’s skin at the time of hospital discharge. Patients will be followed for a total of 1 year from hospital discharge.

Study Design

Multicentre, prospective cohort study

Primary Endpoint

Occurrence of subclinical AF ≥30 minutes in duration within 30 days of hospital discharge

Number of Patients

240

Number of Sites

3

Number of Countries

1

Study Period

2018-2020

Principal Investigator

Dr. Jorge Wong, Dr. Stuart Connolly

Program Manager

Heather Beresh

Research Coordinator

Nazneen Solkar (Jr.RC), Andrea Thornton (Sr.RC)