Prevention of Stroke in Patients with Atrial Fibrillation with Aggessive Treatment of Blood Pressure: A Pilot Study
To compare current guideline-based treatment of blood pressure (target ? 140/90) to an aggressive treatment of blood pressure (target ? 120/80) for the prevention of stroke in AF patients. Patients with atrial fibrillation who have high blood pressure will be invited to participate from 4 clinical centres across Canada. Patients will be assigned to either usual care (blood pressure treated to the current guideline-based target of less than 140/90) or aggressive treatment (blood pressure treated to a level of less than 120/80) and will have 5 visits during six months to achieve this target. The outcome of this pilot phase is to determine the actual achieved blood pressure at 6 and 12 months in the two treatment groups, the difference in blood pressure between groups, the rate of adverse events (if any) in both groups and the feasibility of recruiting eligible study patients.
Feasibility, Ability to comply with blood pressure therapy, Ability to reach target blood pressure goals, Validate the use of automatic blood pressure devices in patients with persistent of permanent AF compared to standard office measures