Research

NeuroVISION

Official Title

Detection and Neurological impact of cerebrovascular events In non-cardiac Surgery Patients: A cohort evaluation Study

Status

Ongoing

Overview

To characterize the epidemiology, incidence, impact, and risk factors of covert stroke in adults undergoing noncardiac surgery. We will determine the incidence of acute covert stroke using an MRI study of the brain in the days following noncardiac surgery. The primary objective of the NeuroVISION study is to characterize the impact of postoperative covert stroke on neurocognitive function 1 year after elective noncardiac surgery.

Study Design

Observational prospective cohort

Primary Endpoint

Primary outcome measure: Postoperative cognitive dysfunction. Secondary outcome measures: Incidence of covert stroke, postoperative delirium, physical function, quality of life, depressive symptoms, clinical outcomes.

Number of Patients

1500

Number of Sites

15

Number of Countries

10

Study Period

2014–2017

Principal Investigator

P.J. Devereaux, Marko Mrkobrada

Program Manager

Shirley Pettit

Research Coordinator

Ingrid Copland

Collaborators

•    CIHR
•    Health and Medical Research Fund, Food and Health Bureau, Hong Kong