DEcreasing POStoperatIve Blood Loss by Topical vs. Intravenous Tranexamic Acid in OpeN Cardiac Surgery
To determine in patients undergoing on-pump cardiac surgery, whether topical tranexamic acid (intra-pericardial/mediastinal delivery) compared to the usual intravenous TxA administration reduces the proportion of patients receiving inhospital red blood cell transfusion.
Single-centre randomized controlled clinical trial
The proportion of patients receiving in-hospital red blood cell transfusion
Andre Lamy, PJ Devereaux, Richard Whitlock, Yannick Lemanach, Emilie Belley-Cote, Julian Own, Jessica Spence, Michael McGillion, Tomas VanHelder, Alison Fox-Robichaud