Prevalence of Sub-Clinical Atrial Fibrillation Using an Implantable Cardiac Monitor in Patient with Cardiovascular Risk Factors (ASSERT-II)
Patients with known cardiovascular risk factors and left atrial enlargement, but without prior AF will have a continuous ECG monitor implanted (St. Jude Medical ConfirmÂ® Implantable Cardiac Monitor) to detect the incidence of sub-clinical AF and study the relationship between sub-clinical AF and left atrial volume and other potential predictors. Patients will be recruited from a variety of clinical settings (HF clinics, stroke clinics, diabetes clinics, pre-op and pre-catheterization clinics) and in many cases the implant can be done in conjunction with a planned surgery or procedure. All patients will be followed at 1, 3, 6 and 9 months and then undergo a final visit at 18 months of follow-up or after the last patient has been followed for 9 months (whichever comes first).
Cohort study – Patients with known cardiovascular risk factors and left atrial enlargement, but without prior AF will have a continuous ECG monitor implanted (St. Jude Medical Confirm® Implantable Cardiac Monitor)
Time to AF, Prevalence of AF, Tolerability of long term monitoring, Proportion of patients who receive anticoagulation therapy, Cost-effectiveness of prolonged external loop monitoring as a strategy for stroke prevention, Burden of atrial arrhythmias in patients with AF, Prevalence of AF episodes of at least 30 seconds.
Stuart Connolly, Jeff Healey, Marco Alings