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Research

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AFOTS

Official Title

Atrial Fibrillation Occurring Transiently with Stress (AFOTS)

Status

Ongoing

Overview

Atrial fibrillation (AF) often occurs transiently in the setting of an acute stressor (e.g. medical illness or surgery). Uncertainly exists as to whether AF Occurring Transiently with Stress (AFOTS) is secondary to a reversible precipitant and is benign, or is a first presentation of paroxysmal AF and associated with a risk of stroke. AFOTS is a common occurrence (up to 15-40% in intensive care), but there is a lack of evidence to guide its management and guidelines have called for further research in this area. The objective of this study is to use a sensitive strategy to determine the rate of recurrent AF among patients who experienced AFOTS following non-cardiac surgery or medical illness, compared to matched controls.

Study Design

Observational study of two cohorts of 138 patients each plus matched controls

Primary Endpoint

Recurrent Atrial Fibrillation within 12 months

Number of Patients

276

Number of Sites

3

Number of Countries

1

Study Period

2017-2019

Principal Investigator

Dr. William F. McIntyre, Dr. Jeff S. Healey

Program Manager

Heather Beresh

Research Coordinator

Natalie Maystrenko

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