Atrial Fibrillation Clopidogrel Trial with ASA for Prevention of Vascular Events
To determine the efficacy of clopidogrel plus ASA versus ASA alone in patients with AF and with at least 1 risk factor for stroke who have a contraindication for other oral anticoagulation.
Randomized, double-blind, efficacy study, placebo controlled superiority trial.
Composite outcome of stroke, non-CNS systemic embolism, myocardial infarction or vascular death
Number of Patients
Number of Sites
Number of Countries
Heather Beresh, Laura Bonilla
- Lamy A, Tong W, Gao P, Chrolavicius S, Gafni A, Yusuf S, Connolly SJ. The cost of clopidogrel use in atrial fibrillation in the ACTIVE-A trial. Can J Cardiol. 2012 Jan-Feb;28(1):95-101. doi: 10.1016/j.cjca.2011.08.112. Epub 2011 Oct 8.
- ACTIVE Investigators, Connolly SJ, Pogue J, Hart RG, Hohnloser SH, Pfeffer M, Chrolavicius S, Yusuf S. Effect of clopidogrel added to aspirin in patients with atrial fibrillation. N Engl J