Research > Networks


CANNeCTIN – the Canadian Network and Centre for Trials Internationally – is a national network funded by the CIHR/CFI Clinical Research Initiative program to improve the prevention and treatment of cardiac and vascular diseases and diabetes. CANNeCTIN is jointly led by Dr. Salim Yusuf, from Hamilton Health Sciences and McMaster University, and Dr. John Cairns, from the University of British Columbia. CANNeCTIN includes investigators with expertise in cardiology, diabetes, obesity, cardiac surgery, anaesthesia, internal medicine, epidemiology, genetics and biostatistics. The vision of the network is that Canadian investigators and institutions will increasingly be internationally recognized as developers and leaders of high impact clinical research studies in cardiovascular disease and diabetes. CANNeCTIN’s national coordinating centre is located at the Population Health Research Institute (PHRI) of Hamilton Health Sciences and McMaster. The studies listed below received initial seed funding for pilot phases with most being successfully launched as full studies.

For more information please visit the CANNeCTIN website



  • The ARVC Registry (Coordinated externally)




  • Heart Failure and Conditioned Nutritional Deficiency in the Myocardium (Coordinated externally)
  • IMPI
  • POISE – 2
  • Understanding the Increased Cardiovascular Risk after Preeclampsia/Eclampsia (Coordinated externally)


The Canadian Stroke Prevention Intervention Network (C-SPIN) will develop actionable strategies that will make Canada a global leader in clinical stroke research; ensure sustainability of these efforts through strategies to recruit, train, support, and retain clinical scientists; and, in collaboration with other networks, government, and stakeholder groups, implement strategies to reduce the incidence of embolic stroke in Canada by 10% within ten years. C-SPIN brings together a nation-wide multidisciplinary team of cardiologists, neurologists, cardiac surgeons, emergency room physicians, family practitioners, pharmacists, statisticians, methodologists, knowledge translation (KT) experts, and population scientists to pursue a common goal of a major reduction in stroke by means of shared expertise, resources, and harmonized research efforts. C-SPIN will also support the recruitment and retention of the next generation of Canadian clinical researchers in this field. C-SPIN will answer challenging questions that will revolutionize our understanding of AF and stroke, improve healthcare strategies, and reduce the rate of stroke among Canadians.

For more information please visit the C-SPIN website

C-SPIN Studies

CVCD Alliance

The Canadian Alliance for Healthy Hearts and Minds

6 Canadian Partnership for Tomorrow Project (CPTP) cohorts:

  • British Columbia Generations Project (BCGP)
  • Alberta Tomorrow Project
  • Ontario Health Study
  • Atlantic Partnership for Tomorrow’s Health (APATH)
  • CVCD Alliance

2 Partner Cohorts:

1 New Aboriginal Participants Cohort:

  • Working with 10 communities across Canada

Bariatric Registry