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Photo for ORCHID

ORCHID

Official Title

Ontario Registry of Chronic Myeloproliferative Neoplasms and Incident Cardiovascular Disease

Overview

ORCHID is a multi-centre prospective observational registry of patients with chronic myeloproliferative neoplasms (MPN) recruited within one year of diagnosis. Its goal is to inform the epidemiology and course of MPNs in the contemporary context. Specifically, as MPN survival improves, and with the advent of treatments that may have cardiovascular adverse effects, there is a need to better understand the evolving epidemiology of MPNs. The creation of this Registry will inform the true incidence of vascular disease in the Tyrosine Kinase Inhibitors (TKI) treated Chronic Myeloid Leukemia (CML), Polycythemia vera (PV), Primary myelofibrosis (PMF) and Essential Thrombocytosis (ET) patient populations.

Study Design

Prospective Registry

Number of Patients

1500

Number of Sites

15

Number of Countries

1

Principal Investigator

Darryl Leong and Chris Hillis – Scientific Chair: Sonia Anand

Program Manager

Dipika Desai

Collaborators

Novartis Canada