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Research

Photo for VISION Registry

VISION Registry

Official Title

Vascular events in noncardiac Surgery patIents cOhort evaluatioN (VISION) Study

Status

Ongoing

Overview

To collect international data regarding major adverse vascular events. during non-cardiac surgery. The increase in elderly patients undergoing surgery, the change in the invasiveness of some surgical interventions, and the limitations of previous research, contribute to uncertainty about the current incidence of major vascular events in patients undergoing noncardiac surgery. Further, uncertainty exists regarding the optimal clinical risk estimation model for predicting major perioperative vascular events. There is promising but inconclusive evidence that troponin measurements after surgery may allow physicians to avoid missing MIs and predict mortality in the first year after surgery. This large international cohort study will inform these issues.

Study Design

Cohort study – prospective, multicentre international study of consecutive patients > 45 years of age undergoing noncardiac surgery.

Primary Endpoint

Primary outcome is a composite of vascular death, nonfatal myocardial infarction, nonfatal cardiac arrest, and nonfatal stroke. Secondary outcomes include all of the individual components of the composite and each of: cardiac revascularization procedures, congestive heart failure, new clinically important atrial fibrillation, deep venous thrombosis, pulmonary embolus, re-hospitalization for vascular reasons, amputation, bleeding, pneumonia, dialysis, new diagnosis of diabetes, and sepsis/infection. Not adjudicated.

Number of Patients

40000

Number of Sites

28

Number of Countries

15

Study Period

2008

Principal Investigator

PJ Devereaux

Program Manager

Not Applicable

Research Coordinator

Shirley Pettit