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Simple warfarin dosing algorithm vs computer anticoaqualation management system

Official Title

Randomized comparison of warfarin dosing quality between the DAWN AC commercial computer program and the validated simple dosing algorithm used at Hamilton General Hospital anticoagulation clinic

Status

Completed

Study Design

RCT

Primary Endpoint

Time in therapeutic INR range

Number of Patients

1068

Number of Sites

1

Number of Countries

1

Study Period

2009–2010

Principal Investigator

Robby Nieuwlaat, Stuart J Connolly

Program Manager

Not Applicable

Research Coordinator

Not Applicable

Collaborators

Hubers LM, Spyropoulos AC, Eikelboom JW, Connolly BJ, Van Spall HG, Schulze KM, Cuddy SM, Stehouwer AC, Schulman S

Key Publications

Nieuwlaat R, Hubers LM, Spyropoulos AC, Eikelboom JW, Connolly BJ, Van Spall HG, Schulze KM, Cuddy SM, Stehouwer AC, Schulman S, Connolly SJ. Randomised comparison of a simple warfarin dosing algorithm versus a computerised anticoagulation management system for control of warfarin maintenance therapy. Thromb Haemost. 2012;108(6):1228-35.