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Research

Photo for SECURE

SECURE

Official Title

The Study to Evaluate Carotid Ultrasound Changes in Patients Treated
With Ramipril and Vitamin E (SECURE)

Status

Completed

Overview

To evaluate the effects of long-term treatment with the angiotensin-converting enzyme inhibitor ramipril and vitamin E on atherosclerosis progression in high-risk patients.

Study Design

Randomized, double-blind with parallel group designs and a 3X2 factorial design

Primary Endpoint

Atherosclerosis progression

Number of Patients

732

Number of Sites

6

Number of Countries

1

Study Period

1993–1995

Principal Investigator

Eva Lonn

Program Manager

Not Applicable

Research Coordinator

Jackie Bosch