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Research

Photo for PAPA - CABG

PAPA - CABG

Official Title

Pilot Study of Preoperative Aspirin and Postoperative Clopidogrel’s Effects on Graft Patency and Cardiac Events in Coronary Artery Bypass Surgery

Status

Completed

Overview

To demonstrate that it is feasible to recruit patients and to use a new test called “CT angiography” to determine whether the bypass grafts are still working or have become blocked.

Study Design

Randomized, double-blind, treatment, placebo control, parallel group design, safety/efficacy.

Primary Endpoint

Graft patency, MI, Death, Stroke. Secondary Endpoint: Bleeding, Transfusion, Re-exploration, Platelet function tests. Not adjudicated.

Number of Patients

150

Number of Sites

1

Number of Countries

1

Study Period

2007–2008

Principal Investigator

John Eikelboom

Program Manager

Not Applicable

Research Coordinator

Deb Sloane