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Research

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NIATH

Official Title

A preliminary study of Non-Invasive measures of ATHerosclerosis in children at high risk of developing atherosclerosis

Status

Completed

Overview

To determine if non-invasive measures of atherosclerosis will be abnormal in children with increased risk for developing coronary artery disease, including children with hyperlipidemia, with diabetes (Type 1 or 2) and who are obese.

Study Design

Cross-sectional study comparing cardiovascular risk factors and non-invasive measures of atherosclerosis in children with conditions that are associated with increased cardiovascular risk (hyperlipidemia, obesity and diabetes (Types 1 & 2)).

Primary Endpoint

Primary: IMT & BAR measures in children age 5 – 18 years and measures of cardiovascular risk, obesity and diabetes. Secondary: Measures of environmental factors and Family History

Number of Patients

200

Number of Sites

1

Number of Countries

1

Study Period

2003–2013

Principal Investigator

Eva Lonn, Katherine Morrison

Program Manager

Sumathy Rangarajan

Research Coordinator

Not Applicable

Collaborators

CIHR