To directly compare the body composition, body fat distribution, and morphological and functional features of adipose tissue and skeletal muscle between South Asians and European Caucasians.
Prospective cross-sectional case-control study
The primary objective of this prospective cross-sectional case-control study is to determine differences among age, sex, and BMI-matched people of South Asian and European Caucasians in body fat composition. The secondary objectives of this study are to determine differences among age, sex, and BMI-matched people of South Asian and European Caucasians in visceral adiposity, adipose tissue morphology, inflammation and adipokine production, skeletal muscle lipid content, fatty acid oxidation and mitochondrial capacity.
Anand SS, Tarnopolsky MA, Rashid S, Schulze KM, Desai D, Mente A, Rao S, Yusuf S, Gerstein HC, Sharma AM. Adipocyte hypertrophy, fatty liver and metabolic risk factors in South Asians: the Molecular Study of Health and Risk in Ethnic Groups (mol-SHARE). PLoS One 2011; 6(7): e22112.