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Research

Photo for DERLA STEMI

DERLA STEMI

Official Title

Delayed educational reminders for long-term medication adherence in ST-elevation myocardial infarction (DERLA-STEMI): Protocol for a pragmatic, cluster-randomized controlled trial

Status

Completed

Overview

to decline over time. Discontinuation of cardiac medications in such patients is associated with increased mortality

Study Design

Pragmatic, cluster-randomised controlled trial, with blinded outcomeassessment

Primary Endpoint

Efficacy Study
The primary outcome is the proportion of patients who report in a phone interview taking all relevant classes of cardiac medications at twelve months. Secondary outcomes to be measured at three and twelve months include proportions of patients who report: actively taking each cardiac medication class of interest (item-by-item); stopping medications due to side effects; taking one or two or three medication classes concurrently; a perfect Morisky Medication Adherence Score for cardiac medication compliance; and having a discussion with their family physician about long-term adherence to cardiac medications.

Number of Patients

500

Number of Sites

1

Number of Countries

1

Study Period

2011–2013

Principal Investigator

JD Schwalm

Program Manager

Not Applicable

Research Coordinator

Not Applicable

Key Publications

Ivers NM, Schwalm JD, Grimshaw JM, Witteman H, Taljaard M, Zwarenstein M, Natarajan MK. Delayed educational reminders for long-term medication adherence in ST-elevation myocardial infarction (DERLA-STEMI): protocol for a pragmatic, cluster-randomized controlled trial. Implement Sci. 2012 Jun 9;7:54. doi: 10.1186/1748-5908-7-54.