
Current Positions
- Principal Investigator – Stroke & Cognition Program, Population Health Research Institute
- Professor- Division of Neurology, Department of Medicine, McMaster University
Bio
Dr. Hart is the leading Principal Investigator for the Stroke program at the Population Health Research Institute. He is a Vascular Neurologist and Professor of Medicine (Neurology) at McMaster University and Hamilton Health Sciences, After completing a fellowship in cerebrovascular disease at the Oregon Health Sciences University, he spent most of his career at the University of Texas Health Science Center in San Antonio before relocating to McMaster University in September 2011. He has a long-standing interest in stroke, stroke research, and clinical trials. He has directed several randomized clinical trials serving as the principal investigator of the NIH/NINDS-sponsored Stroke Prevention in Atrial Fibrillation (SPAF) I, II and III trials (1987-2000) and co-principal investigator of the NIH/NINDS-sponsored Secondary Prevention of Small Subcortical Strokes (SPS3) randomized trials (2001-2013). Antithrombotic therapies to prevent stroke in atrial fibrillation and especially novel oral anticoagulants are areas of special interest. He has published more than 250 articles in peer-reviewed journals.
Research Interests
- Directed several randomized clinical trials serving as the principal investigator of the NIH/NINDS-sponsored Stroke Prevention in Atrial Fibrillation (SPAF) I, II and III trials (1987-2000) and has participated in many others (NASCET, TASS, CATS, CAPRIE, EC-IC Bypass, Canadian-American Persantine Trial, STAT, SPARCL, MATCH, Profess)
- Coordinator of the Cerebral Embolism Study Group (1981-1984), Cerebral Embolism Task Force (1986-1996) and Stroke Risk in Atrial Fibrillation Working Group (2005-8)
- Co-principal investigator of the NIH/NINDS-sponsored Secondary Prevention of Small Subcortical Strokes (SPS3) trial
- Special consultant to the NINDS/NIH Clinical Trials Group (2001-2008)
- Member of the Operations and Stroke Advisory Committees of the AVERROES trial testing apixaban in atrial fibrillation. Antithrombotic therapies to prevent stroke in atrial fibrillation and especially novel oral anticoagulants are areas of special research interest
- Co-principal investigator of the NAVIGATE ESUS international randomized trial testing rivaroxban vs. aspirin in patients with embolic strokes of undetermined source.
- Stroke & Cognitive Function
- ESUS
Publications are listed in chronological order by descending date. Link takes user to pubMed for publication details.
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The t1 pelvic angle, a novel radiographic measure of global sagittal deformity, accounts for both spinal inclination and pelvic tilt and correlates with health-related quality of life.
Source: J Bone Joint Surg Am -
Proximal Junctional Kyphosis and Failure Following Spinal Deformity Surgery: A Systematic Review of the Literature as a Background to Classification Development.
Source: Spine (Phila Pa 1976) -
Embolic strokes of undetermined source: support for a new clinical construct-Authors’ reply.
Source: Lancet Neurol -
Functional Limitations due to Stiffness as a Collateral Impact of Instrumented Arthrodesis of the Lumbar Spine.
Source: Spine (Phila Pa 1976) -
Clinical correlates of infarct shape and volume in lacunar strokes: the secondary prevention of small subcortical strokes trial.
Source: Stroke -
Risk of ischaemic stroke according to pattern of atrial fibrillation: analysis of 6563 aspirin-treated patients in ACTIVE-A and AVERROES.
Source: Eur Heart J -
T1 pelvic angle (TPA) effectively evaluates sagittal deformity and assesses radiographical surgical outcomes longitudinally.
Source: Spine (Phila Pa 1976) -
Predictors of mortality in patients with lacunar stroke in the secondary prevention of small subcortical strokes trial.
Source: Stroke -
Anticoagulation in Patients Aged ?75 years with Atrial Fibrillation: Role of Novel Oral Anticoagulants.
Source: Cardiol Ther -
Life Expectancy and Metastatic Spine Scoring Systems: An Academic Institutional Experience.
Source: J Spinal Disord Tech -
Intraoperative neurophysiological monitoring in anterior lumbar interbody fusion surgery.
Source: J Clin Neurophysiol -
Posterior fixation without debridement for vertebral body osteomyelitis and discitis.
Source: Neurosurg Focus -
Autonomous in situ measurements of seawater alkalinity.
Source: Environ Sci Technol -
Bone mineral density and donor age are not predictive of femoral ring allograft bone mechanical strength.
Source: J Orthop Res -
Lacunar strokes in patients with diabetes mellitus: risk factors, infarct location, and prognosis: the secondary prevention of small subcortical strokes study.
Source: Stroke -
151 Intermediate dosing of recombinant human bone morphogenetic protein-2 improves fusion rates with no increase in major complications but does not improve health related quality of life for adult spinal deformity at minimum 2 years: a prospective, mul
Source: Neurosurgery -
117 Outcomes of Operative and Nonoperative Treatment for Adult Spinal Deformity: A Prospective, Multicenter Matched and Unmatched Cohort Assessment with Minimum 2-Year Follow-up.
Source: Neurosurgery -
Plasmodium yoelii vitamin B5 pantothenate transporter candidate is essential for parasite transmission to the mosquito.
Source: Sci Rep -
Modification of outcomes with aspirin or apixaban in relation to female and male sex in patients with atrial fibrillation: a secondary analysis of the AVERROES study.
Source: Stroke -
Vitamin K antagonists and risk of subdural hematoma: meta-analysis of randomized clinical trials.
Source: Stroke -
Clinical-MRI correlations in a multiethnic cohort with recent lacunar stroke: the SPS3 trial.
Source: Int J Stroke -
Patients with adult spinal deformity treated operatively report greater baseline pain and disability than patients treated nonoperatively; however, deformities differ between age groups.
Source: Spine (Phila Pa 1976) -
Prevalence and type of cervical deformity among 470 adults with thoracolumbar deformity.
Source: Spine (Phila Pa 1976) -
Complications and intercenter variability of three-column osteotomies for spinal deformity surgery: a retrospective review of 423 patients.
Source: Neurosurg Focus -
Stroke prevention in atrial fibrillation: Commentary regarding the AAN’s evidence-based guideline update.
Source: Neurol Clin Pract -
Surgical treatment of pathological loss of lumbar lordosis (flatback) in patients with normal sagittal vertical axis achieves similar clinical improvement as surgical treatment of elevated sagittal vertical axis: clinical article.
Source: J Neurosurg Spine -
Adverse events recording and reporting in clinical trials of cervical total disk replacement.
Source: Instr Course Lect -
Developing a toolkit for comparing safety in spine surgery.
Source: Instr Course Lect -
Liposuction for Submental Lymphedema Improves Appearance and Self-Perception in the Head and Neck Cancer Patient.
Source: Otolaryngol Head Neck Surg -
Likelihood of reaching minimal clinically important difference in adult spinal deformity: a comparison of operative and nonoperative treatment.
Source: Ochsner J -
Embolic strokes of undetermined source: the case for a new clinical construct.
Source: Lancet Neurol -
Revision Surgery After Three-Column Osteotomy in 335 Adult Spinal Deformity Patients: Inter-Center Variability and Risk Factors.
Source: Spine (Phila Pa 1976) -
High-grade spondylolisthesis treated using a modified Bohlman technique: results among multiple surgeons.
Source: J Neurosurg Spine -
CO(2) laser versus cold steel margin analysis following endoscopic excision of glottic cancer.
Source: J Otolaryngol Head Neck Surg -
Does recombinant human bone morphogenetic protein-2 use in adult spinal deformity increase complications and are complications associated with location of rhBMP-2 use? A prospective, multicenter study of 279 consecutive patients.
Source: Spine (Phila Pa 1976) -
Comparison of patient and surgeon perceptions of adverse events after adult spinal deformity surgery.
Source: Spine (Phila Pa 1976) -
A case of bilateral internal auditory canal osteomas.
Source: Ear Nose Throat J -
Long-term functional donor site morbidity of the free radial forearm flap in head and neck cancer survivors.
Source: J Otolaryngol Head Neck Surg -
ASA failure: does the combination ASA/clopidogrel confer better long-term vascular protection?
Source: Neurology -
Rates of thyroid malignancy by FNA diagnostic category.
Source: J Otolaryngol Head Neck Surg -
Illness Apprehension, Depression, Anxiety, and Quality of Life in Liver Transplant Candidates: Implications for Psychosocial Interventions.
Source: Psychosomatics -
Does Recombinant Human Bone Morphogenetic Protein-2 (rhBMP-2) Use in Adult Spinal Deformity (ASD) Increase Complications and Are Complications Associated With Location of rhBMP-2 Use?: A Prospective, Multicenter Study of 279 Consecutive Patients.
Source: Spine (Phila Pa 1976) -
Direct-acting oral anticoagulants: the brain gets a break.
Source: JAMA Neurol -
The Relationship between Marital Status and Psychological Resilience in Chronic Pain.
Source: Pain Res Treat -
Stroke prevention in older adults with atrial fibrillation.
Source: CMAJ -
Is lower socioeconomic status associated with more advanced thyroid cancer stage at presentation? A study in two Canadian centers.
Source: Thyroid -
Rationale and design of the Clarification of Optimal Anticoagulation through Genetics trial.
Source: Am Heart J -
Between red and yellow: evidence of intermediates in a vapochromic Pt(II) salt.
Source: Chem Commun (Camb) -
Reoperation rates and impact on outcome in a large, prospective, multicenter, adult spinal deformity database: clinical article.
Source: J Neurosurg Spine -
A standardized nomenclature for cervical spine soft-tissue release and osteotomy for deformity correction: clinical article.
Source: J Neurosurg Spine -
Can temperate insects take the heat? A case study of the physiological and behavioural responses in a common ant, Iridomyrmex purpureus (Formicidae), with potential climate change.
Source: J Insect Physiol -
Stroke prevention in atrial fibrillation patients with chronic kidney disease.
Source: Can J Cardiol -
Assessment of anticoagulation intensity and management of bleeding with old and new oral anticoagulants.
Source: Can J Cardiol -
Predictors of stroke recurrence in patients with recent lacunar stroke and response to interventions according to risk status: secondary prevention of small subcortical strokes trial.
Source: J Stroke Cerebrovasc Dis -
Identification of decision criteria for revision surgery among patients with proximal junctional failure after surgical treatment of spinal deformity.
Source: Spine (Phila Pa 1976) -
Balancing the benefits and risks of 2 doses of dabigatran compared with warfarin in atrial fibrillation.
Source: J Am Coll Cardiol -
Change in classification grade by the SRS-Schwab Adult Spinal Deformity Classification predicts impact on health-related quality of life measures: prospective analysis of operative and nonoperative treatment.
Source: Spine (Phila Pa 1976) -
The SRS-Schwab adult spinal deformity classification: assessment and clinical correlations based on a prospective operative and nonoperative cohort.
Source: Neurosurgery -
Radiographical spinopelvic parameters and disability in the setting of adult spinal deformity: a prospective multicenter analysis.
Source: Spine (Phila Pa 1976) -
Effect of addition of clopidogrel to aspirin on stroke incidence: Meta-analysis of randomized trials.
Source: Int J Stroke -
Treatment of T1b glottic SCC: laser vs. radiation–a Canadian multicenter study.
Source: J Otolaryngol Head Neck Surg -
Serum biomarkers of papillary thyroid cancer.
Source: J Otolaryngol Head Neck Surg -
Prognostic factors for metastatic cutaneous squamous cell carcinoma of the parotid.
Source: J Otolaryngol Head Neck Surg -
Reduction of airway complications with fluid management protocol in patients undergoing cervical decompression and fusion across the cervicothoracic junction.
Source: Spine (Phila Pa 1976) -
Anticoagulant therapy in acute brain ischaemia.
Source: Lancet Neurol -
Management of high-grade spondylolisthesis.
Source: Neurosurg Clin N Am -
Proximal junctional kyphosis and proximal junctional failure.
Source: Neurosurg Clin N Am -
Efficacy and safety of warfarin vs. antiplatelet therapy in patients with systolic heart failure and sinus rhythm: a systematic review and meta-analysis of randomized controlled trials.
Source: Int J Stroke -
Aspirin therapy and risk of subdural hematoma: meta-analysis of randomized clinical trials.
Source: J Stroke Cerebrovasc Dis -
Modification of outcomes with aspirin or apixaban in relation to CHADS(2) and CHA(2)DS(2)-VASc scores in patients with atrial fibrillation: a secondary analysis of the AVERROES study.
Source: Circ Arrhythm Electrophysiol -
Postoperative prevertebral soft tissue swelling does not affect the development of chronic dysphagia following anterior cervical spine surgery.
Source: Spine (Phila Pa 1976) -
Lumbar Stiffness Disability Index: pilot testing of consistency, reliability, and validity.
Source: Spine J -
Post-traumatic stress symptoms after elective lumbar arthrodesis are associated with reduced clinical benefit.
Source: Spine (Phila Pa 1976) -
Posterior global malalignment after osteotomy for sagittal plane deformity: it happens and here is why.
Source: Spine (Phila Pa 1976) -
Anticoagulants in patients with atrial fibrillation and end-stage renal disease.
Source: Postgrad Med -
Lumbar stiffness as a collateral outcome of spinal arthrodesis: a preliminary clinical study.
Source: Spine J -
The Spine Patient Outcomes Research Trial (SPORT): a continuing return on investment: commentary on an article by Jeffrey A. Rihn, MD, et al.: “The influence of obesity on the outcome of treatment of lumbar disc herniation. analysis of the Spine Patient O
Source: J Bone Joint Surg Am -
Atrial fibrillation in ischemic stroke: predicting response to thrombolysis and clinical outcomes.
Source: Stroke -
Incidence of second cervical vertebral fractures far surpassed the rate predicted by the changing age distribution and growth among elderly persons in the United States (2005-2008).
Source: Spine (Phila Pa 1976) -
Comparison of Patient and Surgeon Perceptions of Adverse Events Following Adult Spinal Deformity Surgery.
Source: Spine (Phila Pa 1976) -
Cognitive impairment in lacunar strokes: the SPS3 trial.
Source: Ann Neurol -
Bleeding during treatment with aspirin versus apixaban in patients with atrial fibrillation unsuitable for warfarin: the apixaban versus acetylsalicylic acid to prevent stroke in atrial fibrillation patients who have failed or are unsuitable for vitamin K
Source: Stroke -
The CHA2DS2-VASc score identifies those patients with atrial fibrillation and a CHADS2 score of 1 who are unlikely to benefit from oral anticoagulant therapy.
Source: Eur Heart J -
Sex, stroke, and atrial fibrillation.
Source: Arch Neurol -
Incidence, Mode, and Location of Acute Proximal Junctional Failures Following Surgical Treatment for Adult Spinal Deformity.
Source: Spine (Phila Pa 1976) -
First record of Zombrus bicolor (Enderlein) (Hymenoptera, Braconidae, Doryctinae) in Western Europe.
Source: Zookeys -
Management of goitre and small nodule disease by Canadian otolaryngologists.
Source: J Otolaryngol Head Neck Surg -
Effects of clopidogrel added to aspirin in patients with recent lacunar stroke.
Source: N Engl J Med -
A low-cost microfluidic chip for rapid genotyping of malaria-transmitting mosquitoes.
Source: PLoS One -
Spontaneous improvement of cervical alignment after correction of global sagittal balance following pedicle subtraction osteotomy.
Source: J Neurosurg Spine -
Anticoagulants in atrial fibrillation patients with chronic kidney disease.
Source: Nat Rev Nephrol -
Effect of addition of clopidogrel to aspirin on mortality: systematic review of randomized trials.
Source: Stroke -
Stroke risk and efficacy of apixaban in atrial fibrillation patients with moderate chronic kidney disease.
Source: J Stroke Cerebrovasc Dis -
Tracheostomy versus mandibular distraction osteogenesis in Canadian children with Pierre Robin sequence: a comparative cost analysis.
Source: J Otolaryngol Head Neck Surg -
Prevalence of atrial fibrillation in patients taking TSH suppression therapy for management of thyroid cancer.
Source: Clin Invest Med -
The impact of standing regional cervical sagittal alignment on outcomes in posterior cervical fusion surgery.
Source: Neurosurgery -
Mechanochemical and solution synthesis, X-ray structure and IR and 31P solid state NMR spectroscopic studies of copper(I) thiocyanate adducts with bulky monodentate tertiary phosphine ligands.
Source: Dalton Trans -
Risk factors for major peri-operative complications in adult spinal deformity surgery: a multi-center review of 953 consecutive patients.
Source: Eur Spine J -
T2 glottic carcinoma: analysis of recurrences in 36 cases undergoing primary transoral laser microsurgery resection.
Source: J Otolaryngol Head Neck Surg -
Reducing the risk of recurrent stroke in patients with AF.
Source: Lancet Neurol -
Clinical features and racial/ethnic differences among the 3020 participants in the Secondary Prevention of Small Subcortical Strokes (SPS3) trial.
Source: J Stroke Cerebrovasc Dis -
Predictors of lowering SBP to assigned targets at 12 months in the Secondary Prevention of Small Subcortical Strokes study.
Source: J Hypertens -
Hyalinizing trabecular tumour: review and new insights into the molecular biology.
Source: J Otolaryngol Head Neck Surg -
Intracranial hemorrhage in atrial fibrillation patients during anticoagulation with warfarin or dabigatran: the RE-LY trial.
Source: Stroke -
Sagittal realignment failures following pedicle subtraction osteotomy surgery: are we doing enough?: Clinical article.
Source: J Neurosurg Spine -
Symptoms of post-traumatic stress following elective lumbar spinal arthrodesis.
Source: Spine (Phila Pa 1976) -
Pulmonary complications after major head and neck surgery: A retrospective cohort study.
Source: Laryngoscope -
Antithrombotic therapy for stroke prevention in atrial fibrillation and mechanical heart valves.
Source: Am J Hematol -
Preliminary biomechanical proof of concept for a hybrid locking plate/variable pitch screw construct for anterior fixation of type II odontoid fractures.
Source: Spine (Phila Pa 1976) -
Apixaban versus aspirin in patients with atrial fibrillation and previous stroke or transient ischaemic attack: a predefined subgroup analysis from AVERROES, a randomised trial.
Source: Lancet Neurol -
Hyperparathyroidism-jaw tumor syndrome.
Source: Head Neck -
Diagnostic accuracy and safety of fine-needle aspiration biopsy of the parapharyngeal space.
Source: Diagn Cytopathol -
Commentary on: Page M, Taylor J, Blenkin M. Forensic identification science evidence since Daubert: Part II–judicial reasoning in decisions to exclude forensic identification evidence on grounds of reliability. J Forensic Sci 2011;56(4):913-7.
Source: J Forensic Sci -
A Portable Analyzer for Pouch-Actuated, Immunoassay Cassettes.
Source: Sens Actuators B Chem -
Universal tracer monitored titrations.
Source: Anal Chem -
Net clinical benefit of adding clopidogrel to aspirin therapy in patients with atrial fibrillation for whom vitamin K antagonists are unsuitable.
Source: Ann Intern Med -
Dynamic changes of the pelvis and spine are key to predicting postoperative sagittal alignment after pedicle subtraction osteotomy: a critical analysis of preoperative planning techniques.
Source: Spine (Phila Pa 1976) -
Acute reciprocal changes distant from the site of spinal osteotomies affect global postoperative alignment.
Source: Adv Orthop -
Multicenter validation of a formula predicting postoperative spinopelvic alignment.
Source: J Neurosurg Spine -
Acknowledging the elephant in the room: conflict of interest in industry-sponsored clinical research.
Source: Spine J -
Warfarin in atrial fibrillation patients with moderate chronic kidney disease.
Source: Clin J Am Soc Nephrol -
Electrochemical behaviour and voltammetric sensitivity at arrays of nanoscale interfaces between immiscible liquids.
Source: Analyst -
Wait times for head and neck cancer patients in the Maritime provinces.
Source: J Otolaryngol Head Neck Surg -
Low-grade myofibroblastic sarcomas of the soft palate and oral tongue.
Source: J Otolaryngol Head Neck Surg -
Cervical disc replacement shows compelling difference in adjacent-level ossification development.
Source: J Bone Joint Surg Am -
Cardiovascular disease in chronic kidney disease. A clinical update from Kidney Disease: Improving Global Outcomes (KDIGO).
Source: Kidney Int -
A self-heating cartridge for molecular diagnostics.
Source: Lab Chip -
What’s new in stroke? The top 10 studies of 2009-2011: part II.
Source: Pol Arch Med Wewn -
What’s new in stroke? The top 10 studies of 2009-2011: part I.
Source: Pol Arch Med Wewn -
Changes in thoracic kyphosis negatively impact sagittal alignment after lumbar pedicle subtraction osteotomy: a comprehensive radiographic analysis.
Source: Spine (Phila Pa 1976) -
Relationship of donor variables and graft dimension on biomechanical performance of femoral ring allograft.
Source: J Orthop Res -
The unmet need of patients with atrial fibrillation: AVERROES and the novel oral anticoagulants.
Source: Int J Stroke -
Complementary and alternative medicine use in the thyroid patients of a head and neck practice.
Source: Otolaryngol Head Neck Surg -
Review of thromboprophylaxis in otolaryngology-head and neck surgery.
Source: J Otolaryngol Head Neck Surg -
Current practice patterns in the management of glottic cancer in Canada: results of a national survey.
Source: J Otolaryngol Head Neck Surg -
Effect of fibula free flap harvest on the gait of head and neck cancer patients: preliminary results.
Source: J Otolaryngol Head Neck Surg -
Thrombolysis for acute stroke in hemodialysis: international survey of expert opinion.
Source: Clin J Am Soc Nephrol -
Irbesartan in patients with atrial fibrillation.
Source: N Engl J Med -
The Secondary Prevention of Small Subcortical Strokes (SPS3) study.
Source: Int J Stroke -
Improved protein detection on an AC electrokinetic quartz crystal microbalance (EKQCM).
Source: Biosens Bioelectron -
Apixaban in patients with atrial fibrillation.
Source: N Engl J Med -
Incidence of parathyroid tissue in level VI neck dissection.
Source: J Otolaryngol Head Neck Surg -
Regarding article “Guidelines for the management of spontaneous intracerebral hemorrhage: a guideline for healthcare professionals from the American Heart Association/American Stroke Association”.
Source: Stroke -
Rates of infection after spine surgery based on 108,419 procedures: a report from the Scoliosis Research Society Morbidity and Mortality Committee.
Source: Spine (Phila Pa 1976) -
Does vertebral level of pedicle subtraction osteotomy correlate with degree of spinopelvic parameter correction?
Source: J Neurosurg Spine -
Incidence of unintended durotomy in spine surgery based on 108,478 cases.
Source: Neurosurgery -
Total nasal reconstruction: use of a radial forearm free flap, titanium mesh, and a paramedian forehead flap.
Source: J Otolaryngol Head Neck Surg -
Guidelines for the primary prevention of stroke: a guideline for healthcare professionals from the American Heart Association/American Stroke Association.
Source: Stroke -
Official position of the American Academy of Clinical Neuropsychology on serial neuropsychological assessments: the utility and challenges of repeat test administrations in clinical and forensic contexts.
Source: Clin Neuropsychol -
Morbidity and mortality in the surgical treatment of 10,242 adults with spondylolisthesis.
Source: J Neurosurg Spine -
Predictors and prevalence of patients undergoing additional kyphoplasty procedures after an initial kyphoplasty procedure.
Source: Spine J -
Optimal treatment for odontoid fractures in the elderly.
Source: Spine (Phila Pa 1976) -
Executive function, intellectual decline and daily living skills.
Source: Neuropsychol Dev Cogn B Aging Neuropsychol Cogn -
Undifferentiated high-grade pleomorphic sarcoma of the face.
Source: J Otolaryngol Head Neck Surg -
Oncocytic lipoadenoma of the parotid gland with sebaceous differentiation in a 73-year-old male.
Source: J Otolaryngol Head Neck Surg -
Synchronous Thyroid/parathyroid Carcinomas.
Source: J Otolaryngol Head Neck Surg -
Morbidity and mortality in the surgical treatment of six hundred five pediatric patients with isthmic or dysplastic spondylolisthesis.
Source: Spine (Phila Pa 1976) -
The communicating vein in the radial forearm free flap.
Source: Plast Reconstr Surg -
Thoracic adolescent idiopathic scoliosis: selection of fusion level.
Source: J Pediatr Orthop B -
Complication rates of three common spine procedures and rates of thromboembolism following spine surgery based on 108,419 procedures: a report from the Scoliosis Research Society Morbidity and Mortality Committee.
Source: Spine (Phila Pa 1976) -
Variability in tissue bank practices regarding donor and tissue screening of structural allograft bone.
Source: Spine (Phila Pa 1976) -
Double fat plane of the radial forearm free flap and its implications for the microvascular surgeon.
Source: J Otolaryngol Head Neck Surg -
A multicenter, prospective study of a novel nasal EPAP device in the treatment of obstructive sleep apnea: efficacy and 30-day adherence.
Source: J Clin Sleep Med -
Morbidity and mortality in the surgical treatment of 10,329 adults with degenerative lumbar stenosis.
Source: J Neurosurg Spine -
Cognitive function and anticoagulation control in patients with atrial fibrillation.
Source: Circ Cardiovasc Qual Outcomes -
Level VI node size as a predictor of malignancy in papillary thyroid cancer.
Source: J Otolaryngol Head Neck Surg -
Rationale and design of AVERROES: apixaban versus acetylsalicylic acid to prevent stroke in atrial fibrillation patients who have failed or are unsuitable for vitamin K antagonist treatment.
Source: Am Heart J -
Fat graft pedicle stabilization in head and neck microvascular reconstruction.
Source: Plast Reconstr Surg -
Lateral ectopic thyroid goiter with a normally located thyroid.
Source: Thyroid -
Solid-state materials for anion sensing in aqueous solution: highly selective colorimetric and luminescence-based detection of perchlorate using a platinum(II) salt.
Source: Chem Commun (Camb) -
Endoscopic stapling versus external transcervical approach for the treatment of Zenker diverticulum.
Source: J Otolaryngol Head Neck Surg -
A case of autologous microfat grafting in lip reconstruction of a whistle deformity following cancer treatment.
Source: Can J Plast Surg -
Short segment coronal plane deformity after two-level lumbar total disc replacement.
Source: Spine (Phila Pa 1976) -
Is preoperative ultrasonography accurate in measuring tumor thickness and predicting the incidence of cervical metastasis in oral cancer?
Source: Oral Oncol -
Complementary and alternative medicine use in patients presenting to a head and neck oncology clinic.
Source: Head Neck -
A case of reactive arthritis in a Ranger Indoctrination Program (RIP) student.
Source: J Spec Oper Med -
General intellectual decline and daily living skills.
Source: Clin Neuropsychol -
Radiotherapy for T1 and T2 laryngeal cancer: the Dalhousie University experience.
Source: J Otolaryngol Head Neck Surg -
Do current guidelines result in overuse of warfarin anticoagulation in patients with atrial fibrillation?
Source: Ann Intern Med -
Budgets for clinical trials.
Source: Front Neurol Neurosci -
Current status of stroke risk stratification in patients with atrial fibrillation.
Source: Stroke -
Laryngeal reconstruction following CO2 laser surgery for glottic cancer.
Source: Head Neck -
A molecular dynamics simulation interpretation of neutron and x-ray diffraction measurements on single phase Y(2)O(3)-Al(2)O(3) glasses.
Source: J Phys Condens Matter -
Chondrosarcoma of the head and neck: report of 11 cases and literature review.
Source: J Otolaryngol Head Neck Surg -
Do we measure up? Is an objective measuring device necessary for the accurate assessment of oral cavity and oropharyngeal lesions?
Source: J Otolaryngol Head Neck Surg -
2008 Austrian-Swiss-German traveling fellowship tour summary.
Source: J Bone Joint Surg Am -
Effect of clopidogrel added to aspirin in patients with atrial fibrillation.
Source: N Engl J Med -
Arteriovenous malformation of the scalp with cerebral steal.
Source: Head Neck -
Characterization of sandwich-cultured hepatocytes as an in vitro model to assess the hepatobiliary disposition of copper.
Source: Drug Metab Dispos -
Comprehensive analysis of particle motion under non-uniform AC electric fields in a microchannel.
Source: Lab Chip -
What’s new in stroke? The top 10 studies of 2006-2008. Part II.
Source: Pol Arch Med Wewn -
Effect of age on stroke prevention therapy in patients with atrial fibrillation: the atrial fibrillation investigators.
Source: Stroke -
What’s new in stroke? The top 10 studies of 2006-2008. Part I.
Source: Pol Arch Med Wewn -
Stenting of the frontal recess in frontal sinus fractures: an alternative to obliteration.
Source: J Otolaryngol Head Neck Surg -
Eosinophilic mucin rhinosinusitis with skull base erosion: case report and literature review.
Source: J Otolaryngol Head Neck Surg -
Neuroprotection trials in Parkinson’s disease: systematic review.
Source: Mov Disord -
Perioperative complications of combined anterior and posterior cervical decompression and fusion crossing the cervico-thoracic junction.
Source: Spine (Phila Pa 1976) -
AC electrokinetic phenomena generated by microelectrode structures.
Source: J Vis Exp -
Adverse events associated with anterior cervical spine surgery.
Source: J Am Acad Orthop Surg -
Structure of high alumina content Al2O3-SiO2 composition glasses.
Source: J Phys Chem B -
Reduction of traumatic macroglossia with base of tongue corticosteroid injection.
Source: Otolaryngol Head Neck Surg -
Restaurant inspection frequency and food safety compliance.
Source: J Environ Health -
Dentinogenic ghost cell tumor of the maxilla.
Source: Otolaryngol Head Neck Surg -
The role of short-range diffusion in solvent-assisted mechanochemical synthesis of metal complexes.
Source: Dalton Trans -
The prediction of change: normative neuropsychological trajectories.
Source: Clin Neuropsychol -
Swallowing function in patients with base of tongue cancers treated with primary surgery and reconstructed with a modified radial forearm free flap.
Source: Arch Otolaryngol Head Neck Surg -
Leave ’em alone – why continuous variables should be analyzed as such.
Source: Neuroepidemiology -
Proximal junctional acute collapse cranial to multi-level lumbar fusion: a cost analysis of prophylactic vertebral augmentation.
Source: Spine J -
Risks and benefits of oral anticoagulation compared with clopidogrel plus aspirin in patients with atrial fibrillation according to stroke risk: the atrial fibrillation clopidogrel trial with irbesartan for prevention of vascular events (ACTIVE-W).
Source: Stroke -
Did we really need another comparison of warfarin with aspirin? An assessment of the BAFTA trial.
Source: Pol Arch Med Wewn -
Clopidogrel and aspirin versus aspirin alone for the prevention of stroke in patients with a history of atrial fibrillation: subgroup analysis of the CHARISMA randomized trial.
Source: Cerebrovasc Dis -
Enoxaparin thromboprophylaxis in gastric bypass patients: extended duration, dose stratification, and antifactor Xa activity.
Source: Surg Obes Relat Dis -
Nodular fasciitis of the zygoma: A case report.
Source: Can J Plast Surg -
Traumatic spondyloptosis resulting from high-energy trauma concurrent with a tonic-clonic seizure.
Source: Spine J -
Adjusted-dose warfarin versus aspirin for preventing stroke in patients with atrial fibrillation.
Source: Ann Intern Med -
Anticoagulation in atrial fibrillation: selected controversies including optimal anticoagulation intensity, treatment of intracerebral hemorrhage.
Source: J Thromb Thrombolysis -
Variability in rates of arthrodesis for patients with thoracolumbar spine fractures with and without associated neurologic injury.
Source: Spine (Phila Pa 1976) -
Biomechanical comparison of a fully threaded, variable pitch screw and a partially threaded lag screw for internal fixation of Type II dens fractures.
Source: Spine (Phila Pa 1976) -
Sentinel node biopsy in N0 squamous cell carcinoma of the oral cavity and oropharynx in patients previously treated with surgery or radiation therapy: a pilot study.
Source: Arch Otolaryngol Head Neck Surg -
Statistical process control for hospitals: methodology, user education, and challenges.
Source: Qual Manag Health Care -
Use of pelvic incidence as a guide to reduction of H-type spino-pelvic dissociation injuries.
Source: J Orthop Trauma -
Meta-analysis: antithrombotic therapy to prevent stroke in patients who have nonvalvular atrial fibrillation.
Source: Ann Intern Med -
Correlation between rheological properties of zinc carboxylate liquids and molecular structure.
Source: J Phys Chem B -
Spine surgery for lumbar degenerative disease in elderly and osteoporotic patients.
Source: Instr Course Lect -
Mechanical comparison of posterior instrumentation constructs for spinal fixation across the cervicothoracic junction.
Source: Spine (Phila Pa 1976) -
Comparative utility of Barona Formulae, Wtar demographic algorithms, and WRAT-3 reading for estimating premorbid ability in a diverse research sample.
Source: Clin Neuropsychol -
Biomechanical comparison of a novel multilevel hex-head pedicle screw design with a conventional head design.
Source: J Orthop Res -
Control limits for p control charts with small subgroup sizes.
Source: Qual Manag Health Care -
Use of the external jugular vein as the sole recipient vein in head and neck free flap reconstruction.
Source: J Otolaryngol -
High-sensitivity C-reactive protein and soluble CD40 ligand as indices of inflammation and platelet activation in 880 patients with nonvalvular atrial fibrillation: relationship to stroke risk factors, stroke risk stratification schema, and prognosis.
Source: Stroke -
Post-traumatic stress disorder and post-traumatic stress symptoms following critical illness in medical intensive care unit patients: assessing the magnitude of the problem.
Source: Crit Care -
Reliability and validity of blood pressure measurement in the Secondary Prevention of Small Subcortical Strokes study.
Source: Blood Press Monit -
Treatment of warfarin-associated intracerebral hemorrhage: literature review and expert opinion.
Source: Mayo Clin Proc -
Variability in rates of arthrodesis procedures for patients with cervical spine injuries with and without associated spinal cord injury.
Source: J Bone Joint Surg Am -
A simple risk score predicted 7 day stroke risk after transient ischaemic attack.
Source: Evid Based Med -
Case report: vertebral compression fracture in a fused and instrumented lumbar segment.
Source: Clin Orthop Relat Res -
Delayed fracture of fibular strut allograft following multilevel anterior cervical spine corpectomy and fusion.
Source: Spine (Phila Pa 1976) -
National Stroke Association guidelines for the management of transient ischemic attacks.
Source: Ann Neurol -
Divergent thinking in Alzheimer’s and frontotemporal dementia.
Source: Neuropsychol Dev Cogn B Aging Neuropsychol Cogn -
Additive role of plasma von Willebrand factor levels to clinical factors for risk stratification of patients with atrial fibrillation.
Source: Stroke -
American Stroke Association guideline policies.
Source: Stroke -
Primary prevention of ischemic stroke: a guideline from the American Heart Association/American Stroke Association Stroke Council: cosponsored by the Atherosclerotic Peripheral Vascular Disease Interdisciplinary Working Group; Cardiovascular Nursing Counc
Source: Circulation -
Headache improvement through TMD stabilization appliance and self-management therapies.
Source: Cranio -
What’s new in stroke? The top 10 for 2004/05.
Source: J Am Geriatr Soc -
Primary prevention of ischemic stroke: a guideline from the American Heart Association/American Stroke Association Stroke Council: cosponsored by the Atherosclerotic Peripheral Vascular Disease Interdisciplinary Working Group; Cardiovascular Nursing Counc
Source: Stroke -
Failed spine surgery syndrome in the life and career of John Fitzgerald Kennedy.
Source: J Bone Joint Surg Am -
Biarylaniline phenethanolamines as potent and selective beta3 adrenergic receptor agonists.
Source: J Med Chem -
Optimal INR for prevention of stroke and death in atrial fibrillation: a critical appraisal.
Source: Thromb Res -
X and s charts for health care comparisons.
Source: Qual Manag Health Care -
Mechanical stiffness of segmental versus nonsegmental pedicle screw constructs: the effect of cross-links.
Source: Spine (Phila Pa 1976) -
Anticoagulation intensity and stroke during warfarin-use in atrial fibrillation patients.
Source: Stroke -
Reliability and reproducibility of dens fracture classification with use of plain radiography and reformatted computer-aided tomography.
Source: J Bone Joint Surg Am -
A simple risk score predicted 7-day stroke risk after transient ischemic attack.
Source: ACP J Club -
Atrial fibrillation and stroke: four treatment controversies.
Source: Curr Treat Options Neurol -
Variation in surgical decision making for degenerative spinal disorders. Part II: cervical spine.
Source: Spine (Phila Pa 1976) -
Variation in surgical decision making for degenerative spinal disorders. Part I: lumbar spine.
Source: Spine (Phila Pa 1976) -
Perindopril-based blood pressure-lowering reduces major vascular events in patients with atrial fibrillation and prior stroke or transient ischemic attack.
Source: Stroke -
Pedicle screw placement in the thoracic spine: a comparison of image-guided and manual techniques in cadavers.
Source: Spine (Phila Pa 1976) -
Clinical research in primary stroke prevention: needs, opportunities, and challenges.
Source: Neuroepidemiology -
Avoiding central nervous system bleeding during antithrombotic therapy: recent data and ideas.
Source: Stroke -
Occurrence and characteristics of stroke events in the Atrial Fibrillation Follow-up Investigation of Sinus Rhythm Management (AFFIRM) study.
Source: Arch Intern Med -
Impairment of perineal care functions after long fusions of the lumbar spine.
Source: Clin Orthop Relat Res -
Data and safety monitoring in clinical research: a National Institute of Neurologic Disorders and Stroke perspective.
Source: Ann Emerg Med -
Carotid-artery stenting versus endarterectomy.
Source: N Engl J Med -
Comparison of stiffness and failure load of two cervical spine fixation techniques in an in vitro human model.
Source: J Spinal Disord Tech -
Sentinel lymph node biopsy in N0 squamous cell carcinoma of the oral cavity and oropharynx.
Source: Arch Otolaryngol Head Neck Surg -
Evaluation of a HACCP pilot program for the food service industry.
Source: Can J Public Health -
Tracheostomy after anterior cervical spine fixation.
Source: J Trauma -
Segmental motion adjacent to an instrumented lumbar fusion: the effect of extension of fusion to the sacrum.
Source: Spine (Phila Pa 1976) -
Selecting patients with atrial fibrillation for anticoagulation: stroke risk stratification in patients taking aspirin.
Source: Circulation -
The association between delirium and cognitive decline: a review of the empirical literature.
Source: Neuropsychol Rev -
Neuropsychologists diagnose traumatic brain injury.
Source: Brain Inj -
Application of variables control charts to risk-adjusted time-ordered healthcare data.
Source: Qual Manag Health Care -
Predictors of stroke in patients paced for sick sinus syndrome.
Source: J Am Coll Cardiol -
Attention and the stages of pain processing.
Source: Pain Med -
Variations in injury patterns, treatment, and outcome for spinal fracture and paralysis in adult versus geriatric patients.
Source: Spine (Phila Pa 1976) -
Oral anticoagulants vs. aspirin for stroke prevention in patients with non-valvular atrial fibrillation: the verdict is in.
Source: Card Electrophysiol Rev -
Transient ischemic attacks in patients with atrial fibrillation: implications for secondary prevention: the European Atrial Fibrillation Trial and Stroke Prevention in Atrial Fibrillation III trial.
Source: Stroke -
Atrial fibrillation and stroke prevention.
Source: N Engl J Med -
Prognostic value of plasma von Willebrand factor and soluble P-selectin as indices of endothelial damage and platelet activation in 994 patients with nonvalvular atrial fibrillation.
Source: Circulation -
Serum potassium level and dietary potassium intake as risk factors for stroke.
Source: Neurology -
Graft migration or displacement after multilevel cervical corpectomy and strut grafting.
Source: Spine (Phila Pa 1976) -
Antithrombotic therapies for stroke prevention in atrial fibrillation.
Source: Adv Neurol -
Lessons from the Stroke Prevention in Atrial Fibrillation trials.
Source: Ann Intern Med -
Aspirin dosage and thromboxane synthesis in patients with vascular disease.
Source: Pharmacotherapy -
A clinical prediction rule to identify patients with atrial fibrillation and a low risk for stroke while taking aspirin.
Source: Arch Intern Med -
Six-month neuropsychological outcome of medical intensive care unit patients.
Source: Crit Care Med -
Clinical outcomes related to interface type in patients with obstructive sleep apnea/hypopnea syndrome who are using continuous positive airway pressure.
Source: Chest -
Why is WASID an important clinical trial?
Source: Neuroepidemiology -
Electrical stimulation for intraoperative evaluation of thoracic pedicle screw placement.
Source: Spine (Phila Pa 1976) -
Late-developing cerebral arteropathy after pyogenic meningitis.
Source: Arch Neurol -
Cognitive impairment in patients with chronic pain: the significance of stress.
Source: Curr Pain Headache Rep -
Application of attribute control charts to risk-adjusted data for monitoring and improving health care performance.
Source: Qual Manag Health Care -
Percutaneous treatment of osteoporotic spinal compression fractures.
Source: Curr Womens Health Rep -
Enzymatic assay for measurement of intracellular DXG triphosphate concentrations in peripheral blood mononuclear cells from human immunodeficiency virus type 1-infected patients.
Source: Antimicrob Agents Chemother -
Oral anticoagulants vs aspirin in nonvalvular atrial fibrillation: an individual patient meta-analysis.
Source: JAMA -
ABC of antithrombotic therapy: Antithrombotic therapy for cerebrovascular disorders.
Source: BMJ -
Antithrombotic therapy for atrial fibrillation.
Source: BMJ -
Atrial fibrillation, stroke, and acute antithrombotic therapy: analysis of randomized clinical trials.
Source: Stroke -
Comparison between automatic and fixed positive airway pressure therapy in the home.
Source: Am J Respir Crit Care Med -
An assessment of guidelines for prevention of ischemic stroke.
Source: Neurology -
Plasma von Willebrand factor and soluble p-selectin as indices of endothelial damage and platelet activation in 1321 patients with nonvalvular atrial fibrillation: relationship to stroke risk factors.
Source: Circulation -
Making anticoagulation safer.
Source: Neurology -
Correlations for scores on the 180-item version of the MMPI-2 and the Neuroticism scale of the NEO-Personality Inventory.
Source: Psychol Rep -
Do we really need a better way to give heparin in acute cerebral ischemia?
Source: Stroke -
Pre-injury status and adaptation following traumatic brain injury.
Source: Brain Inj -
Synthesis and evaluation of potent and selective beta(3) adrenergic receptor agonists containing acylsulfonamide, sulfonylsulfonamide, and sulfonylurea carboxylic acid isosteres.
Source: J Med Chem -
Cervical facet dislocation: when is magnetic resonance imaging indicated?
Source: Spine (Phila Pa 1976) -
Neurologic manifestations of cardiogenic embolism: an update.
Source: Neurol Clin