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Dr. Robert Hart MD

Photo of Robert Hart
Robert Hart Dr.

Current Positions

  • Principal Investigator – Stroke & Cognition Program, Population Health Research Institute
  • Professor- Division of Neurology, Department of Medicine, McMaster University

Bio

Dr. Hart is the leading Principal Investigator for the Stroke program at the Population Health Research Institute. He is a Vascular Neurologist and Professor of Medicine (Neurology) at McMaster University and Hamilton Health Sciences, After completing a fellowship in cerebrovascular disease at the Oregon Health Sciences University, he spent most of his career at the University of Texas Health Science Center in San Antonio before relocating to McMaster University in September 2011. He has a long-standing interest in stroke, stroke research, and clinical trials. He has directed several randomized clinical trials serving as the principal investigator of the NIH/NINDS-sponsored Stroke Prevention in Atrial Fibrillation (SPAF) I, II and III trials (1987-2000) and co-principal investigator of the NIH/NINDS-sponsored Secondary Prevention of Small Subcortical Strokes (SPS3) randomized trials (2001-2013). Antithrombotic therapies to prevent stroke in atrial fibrillation and especially novel oral anticoagulants are areas of special interest. He has published more than 250 articles in peer-reviewed journals.

Research Interests

  • Directed several randomized clinical trials serving as the principal investigator of the NIH/NINDS-sponsored Stroke Prevention in Atrial Fibrillation (SPAF) I, II and III trials (1987-2000) and has participated in many others (NASCET, TASS, CATS, CAPRIE, EC-IC Bypass, Canadian-American Persantine Trial, STAT, SPARCL, MATCH, Profess)
  • Coordinator of the Cerebral Embolism Study Group (1981-1984), Cerebral Embolism Task Force (1986-1996) and Stroke Risk in Atrial Fibrillation Working Group (2005-8)
  • Co-principal investigator of the NIH/NINDS-sponsored Secondary Prevention of Small Subcortical Strokes (SPS3) trial
  • Special consultant to the NINDS/NIH Clinical Trials Group (2001-2008)
  • Member of the Operations and Stroke Advisory Committees of the AVERROES trial testing apixaban in atrial fibrillation. Antithrombotic therapies to prevent stroke in atrial fibrillation and especially novel oral anticoagulants are areas of special research interest
  • Co-principal investigator of the NAVIGATE ESUS international randomized trial testing rivaroxban vs. aspirin in patients with embolic strokes of undetermined source.
  • Stroke & Cognitive Function
  • ESUS

Publications are listed in chronological order by descending date. Link takes user to pubMed for publication details.