This is a pilot randomized trial of patients with ST elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI) comparing routine manual aspiration thrombectomy and PCI vs. PCI alone to demonstrate the feasibility of performing a large multi-center outcomes trial. Feasibility success will be determined by the ability to recruit 2 patients per site per month and to obtain an assessment of cross-over rates. We plan to proceed to a full clinical trial of approximately 4000 patients with a primary outcome of death, recurrent myocardial infarction, cardiogenic shock or new or worsening congestive heart failure at 180 days.  PIs: Sanjit Jolly (McMaster) and Vladimir Dzavik (U. Toronto)

Study Design: Multi-Center, non-blinded, randomized controlled trial with outcomes adjudicated by assessors who will be blinded to the treatment arm.

Intervention: Manual aspiration thrombectomy with PCI vs. PCI alone.

Length of Study: 1.5 years

# of Patients: 240

Patient Populations: Patients with ST elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI)

Presentations

Available upon study completion.

Main Publications (A full listing of PHRI publications can be found in the 'Media & Publictions' section)