Population Health Research Institute
Study List

TOTAL (Ongoing)
Randomized Trial of Routine Aspiration ThrOmbecTomy with Percutaneous Coronary Intervention (PCI) vs. PCI ALone in Patients with STEMI Undergoing Primary PCI

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 The TOTAL trial aims to determine if the routine use of manual aspiration thrombectomy with the Export® catheter with PCI compared to PCI alone will reduce the incidence of death, recurrent MI, cardiogenic shock or new or worsening NYHA class IV HF at 180 days in patients with STEMI undergoing primary PCI.

Study Design: International, randomized, controlled, parallel group study trial of 4000 patients. Patients will be randomized prior to diagnostic angiography to either Manual Aspiration Thrombectomy followed by PCI or PCI Alone.

Intervention: Manual aspiration thrombectomy with PCI vs. PCI alone.

Length of Study: 2.5 years

# of Patients: 4,000

Patient Populations: Patients with ST elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI)



Available upon study completion.


Main Publications (A full listing of PHRI publications can be found in the 'Media & Publictions' section)

Not available at this time.

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