Population Health Research Institute
Study List

SUPERIOR SVG PATENCY CABG CANNeCTIN  Pilot (ongoing)
SUrgical and Pharmacological novel intERventions to Improve Overall Results of
Saphenous Vein Graft Patency in Coronary Artery Bypass Grafting surgery: An International
Randomized Controlled Clinical Trial

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The ultimate aim of this study is to perform an international multicenter factorial design RCT to see if a novel atraumatic pedicled (no touch) technique of SVG harvesting (surgical arm) and/or the use of oral N-3 polyunsaturated fatty acid (pharmacological arm) improve angiographic patency and clinical outcomes at 1 year compared to conventional SVG harvesting and placebo respectively. This CANNeCTIN-funded pilot study will assess feasibility. PIs: Stephen Fremes and Steve Singh (Sunnybook) and Richard Novick and Michael CHU (UWO)

Study Design:  Factorial Design RCT

Intervention: Novel saphenous vein graft harvesting vs. conventional (single-blinded); N-3 polyunsaturated fatty acid (fish oil) vs. pacebo (double-blinded)

Length of Study:  1.5 years

# of Patients:  50 patients at 8 sites (pilot phase)

Patient Populations: Patients undergoing multiple coronary artery bypass graft surgery.


Presentations

Available upon study completion.


Main Publications (for a full listing of publications, please visit the 'Media and Publications' section)

Not available at this time.

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Population Health Research Institute • Hamilton, Ontario • information@phri.ca