SUPERIOR SVG PATENCY CABG CANNeCTIN Pilot (ongoing)
SUrgical and Pharmacological novel intERventions to Improve Overall Results of
Saphenous Vein Graft Patency in Coronary Artery Bypass Grafting surgery: An International
Randomized Controlled Clinical Trial
The ultimate aim of this study is to perform an international multicenter factorial design RCT to see if a novel atraumatic pedicled (no touch) technique of SVG harvesting (surgical arm) and/or the use of oral N-3 polyunsaturated fatty acid (pharmacological arm) improve angiographic patency and clinical outcomes at 1 year compared to conventional SVG harvesting and placebo respectively. This CANNeCTIN-funded pilot study will assess feasibility. PIs: Stephen Fremes and Steve Singh (Sunnybook) and Richard Novick and Michael CHU (UWO)
Study Design: Factorial Design RCT
Intervention: Novel saphenous vein graft harvesting vs. conventional (single-blinded); N-3 polyunsaturated fatty acid (fish oil) vs. pacebo (double-blinded)
Length of Study: 1.5 years
# of Patients: 50 patients at 8 sites (pilot phase)
Patient Populations: Patients undergoing multiple coronary artery bypass graft surgery.
Available upon study completion.
Main Publications (for a full listing of publications, please visit the 'Media and Publications' section)
Not available at this time.