Population Health Research Institute
Study List

RAAFT (Ongoing)
First Line Radiofrequency Ablation Versus Antiarrhythmic Drugs for Atrial Fibrillation Treatment.

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The purpose of this study is to determine whether catheter-based pulmonary vein isolation is superior to antiarrhythmic drugs as first line therapy in patients with symptomatic paroxysmal recurrent atrial fibrillation not previously treated with therapeutic doses of antiarrhythmic drugs.

Study Design: Treatment, Randomized, Open Label, Active Control, Parallel Assignment, Safety/Efficacy

Intervention: Catheter-based pulmonary vein isolation vs. antiarrhythmic drugs

Length of Study: 4 years

# of Patients: 400

Patient Populations: Atrial fibrillation


Available upon study completion.

Main Publications (for a full listing of publications, please visit the 'Media and Publications' section)

Radiofrequency ablation vs antiarrhythmic drugs as first-line treatment of paroxysmal atrial fibrillation (RAAFT-2): a randomized trial


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Population Health Research Institute • Hamilton, Ontario • information@phri.ca