Population Health Research Institute
Study List

RIVAL (Completed)
RadIal Vs. FemorAL Access for Coronary Intervention Study

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The trial evaluates two strategies for arterial access, femoral vs. radial,  during heart catheterization for acute coronary syndromes The RIVAL study is designed to establish whether the overall benefits versus risks of a radial artery approach justify its routine use in patients undergoing percutaneous coronary intervention. It is anticipated that the radial approach will  reduce the frequency of bleeding events in patients managed with an invasive strategy.   

Study Design: Randomized controlled, parallel group design.

Intervention: Femoral arterial access vs. radial arterial access. 

Length of Study: 3 years

# of Patients: 8,000 (3,500 recruited as of March '09)

Patient Populations: ACS undergoing early PCI.


The late-breaking clinical trial (LBCT) session at the American College of Cardiology 60th Annual Scientific Session and i2 Summit, April 4, 2011, in New Orleans, Louisiana, USA.
A randomized comparison of RadIal Vs. femorAL access for coronary intervention in ACS (RIVAL) (PDF)

Main Publications (for a full listing of publications, please visit the 'Media and Publications' section)

Sanjit S Jolly, Salim Yusuf, John Cairns, Kari Niemelä, Denis Xavier, Petr Widimsky, Andrzej Budaj, Matti Niemelä, Vicent Valentin, Basil S Lewis, Alvaro Avezum, Philippe Gabriel Steg, Sunil V Rao, Peggy Gao, Rizwan Afzal, Campbell D Joyner, Susan Chrolavicius, Shamir R Mehta; Radial versus femoral access for coronary angiography and intervention in patients with acute coronary syndromes (RIVAL): a randomised, parallel group, multicentre trial. The Lancet published Online 04 April, 2011 DOI:10.1016/S0140-6736(11)60404-2 


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