INTERSTROKE (Ongoing)
A Study of the Importance of Conventional and Emerging Risk Factors of Stroke in Different Regions and Ethnic Groups of the World |
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 The INTERHEART study found that nine easily measurable and modifiable risk factors could explain over 90 per cent of the risk of a heart attack globally and in all regions and major ethnic groups of the world. These studies emphasized that avoidance of tobacco, daily consumption of fruits and vegetables and regular exercise could potentially avoid two-thirds of heart disease. The results also indicated that tobacco (smoking even one cigarette per day increases the risk of myocardial infarction (MI) by five per cent) and abnormal lipids were the two most important risk factors globally, and that the markers of abdominal obesity and hip size (waist-to-hip-ratio) are far more predictive than body mass index (BMI) in predicting MI. Furthermore, stress and psychosocial factors were found to be important risk factors for MI.
Study Design: Observational Study.
Intervention: N/A.
Length of Study: 4 years
# of Patients: 24,000
Patient Populations: Population at risk for stroke.
Presentations
Available upon study completion.
Main Publications (for a full listing of publications, please visit the 'Media and Publications' section)
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O'Donnell M, Yusuf S. Global Variation in Stroke: The Need for Large-Scale International Studies. Lancet Neurology 2009;8(4):306-7
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| O'Donnell M, Xavier D, Chin SL, Diener C, Sacco R, Lisheng L, Zhang H, Pias P, Truelsen T, DeVilliers L, Domasceno A, Mondo C, Lanas F, Avezum A, Varigos J, Hankey G, Teal P, Ryglewicz D, Skowronska M, Kapral M, Amoah A, Jaramillo PL, Diaz R, Dans T, Yusuf S; On Behalf of the INTERSTROKE Investigators. INTERSTROKE: A Global Case Control Study of Risk Factors for Stroke. |
| Oczkowski C, O'Donnell M. Reliability of Proxy Respondents for Stroke Patients: A Systematic Review. J of Stroke and Cerebrovasc Dis (2009, In Press) |
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