Population Health Research Institute
Women's Health

Women's Health
Exploring differences in heart disease presentation and diagnosis,
and Metabolic Syndrome related factors between men and women

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The Women's Health program at PHRI is focused on the promotion of women's health in the clinical, education and research domains, with specific reference to cardiovascular disease (CVD). On the clinical front of this program, women with risk factors for CVD or established CVD are diagnosed and treated at the Women's Vascular Clinic at McMaster University Medical Centre in Hamilton.  

This program area is focused on conducting population-based and clinical trials to understand the broad determinants of type-2 diabetes and CVD among women. The program is also focused on studying breast cancer, access to health care among women and the evaluation of treatment effects of specific medical therapies in women with established CVD. The Caring Network - An Interdisciplinary Capacity Enhancement (ICE) grant from the Canadian Institutes of Health Research (CIHR) and Heart and Stroke Foundation of Ontario (HSFO) has allowed the establishment of the Caring Network (2004-2009) at PHRI. The projects in this area explore whether and why women have differing outcomes in acute coronary syndromes and the metabolic syndrome.


Main Publications

Anand SS, Islam S, Rosengren A, Franzosi MG, Steyn K, Yusufali AH, Keltai M, Diaz R, Rangarajan S, Yusuf S; INTERHEART Investigators. Risk factors for myocardial infarction in women and men: insights from the INTERHEART study. Eur Heart J. 2008 Apr;29(7):932-40. Epub 2008 Mar 10.

Keshavarz H, Prabhakaran D, Anand S. Metabolic Risk Factors for vascular disease in women. Greer IA, Ginsberg J, Forbes CD. Editors. Women's Vascular Health. University of Glasgow (In Press).

Aulakh AK, Anand SS. Sex and gender subgroup analyses of randomized trials. Womens Health Issues. 2007 Nov-Dec;17(6):342-50. Epub 2007 Oct 22. Review.

Yusuf S, Anand S. Hormone replacement therapy: a time for pause. CMAJ 2002 Aug 20; 167(4): 357-9.

Caldwell PH, Arthur HM, Natarajan M, Anand SS. Fears and beliefs of patients regarding cardiac catheterization. Soc Sci Med. 2007 Sep;65(5):1038-48. Epub 2007 May 15.

Anand S, Xie C, Mehta S, Franzosi M, Joyner C, Chrolavicius S, Fox K, Yusuf S. Differences in the Management and Prognosis of Women and Men who suffer Acute Coronary Syndromes. J Am Coll Cardiol Nov 15; 46(10): 1845-51.

Anand S, Razak F, Davis A.D., Jacobs R, Vuksan V, Teo K, Yusuf S. Social disadvantage and CVD: development of an index and analysis of age, sex and ethnicity effects. Int J of Epidmiol 2006.

Kreatsoulas C, Anand S.  Considering race/ethnicity and socio-economic status in randomized controlled trials. A commentary on a systematic review generalizing trial findings and tackling health disparities in asthma research. Soc Sci Med. 2009 Jul 27. [Epub ahead of print] No abstract available.


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Population Health Research Institute • Hamilton, Ontario • information@phri.ca